PhD Studentship: Covalent inhibition of streptococcal glucan sucrases to disrupt oral biofilm development

Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and National Biofilms Innovation Centre), Prof. Paul Stoodley (University of Southampton), Dr Rob Howlin (Haleon, industry), Dr David Bradshaw and Dr Ricarda Hawkins (Haleon, industry) Project Description:A fully-funded 4 year National Biofilms Innovation...

Supervisory Team: Prof Ali Tavassoli Project Description:We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. Mutant RAS proteins drive numerous cancers, with their...

Project title: PhD Studentship in Nanophotonics and Metamaterials: Development of Switchable and Programmable Metasurfaces using Novel Materials Supervisory Team: Prof. Otto Muskens; Dr Ioannis ZeimpekisProject description:Metaoptics, the application of metasurface concepts in optical systems, is a rapidly growing field that has the potential to...

Project title: Rapid Development and Testing of Multifunctional Antimicrobial Coatings to Combat Urological Device Infections Supervisory Team: Dr Andrew R. Hamilton; Dr Ali Mosayyebi; Dr Dario CarugoProject description:Urological devices (stents and catheters) are deployed as temporary measures to restore urinary drainage in patients with kidney stones,...

Supervisory Team: Dr N.C. Townsend, Prof D.A. Hudson and Dr J.A. Bowker (industrial)Project descriptionShip model testing is expensive and time consuming. Can we derive hydrodynamic seakeeping and manoeuvring characteristics with focused datasets, eliminating time consuming single variable investigations?In this PhD program you will develop and test novel...

PhD Supervisor: Dr Nema AbdelazimSupervisory Team: Dr Nema AbdelazimProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and commercial skills.We are offering an exciting...

Supervisory Team: Benjamin CameronProject descriptionThis PhD is focussed on a new theoretical/computational method to measure material properties in places where they are really difficult to measure: e.g. in a shock wave, in a shear band, or at a crack tip. These are all of critical importance in many engineering problems such as car crashes, manufacturing...

Supervisory Team: Dr N.C. Townsend, Prof D.A. Hudson and Dr J.A. Bowker (industrial)Project descriptionWave energy can be used to improve the performance of ships and boats. By exploiting hydrodynamically the available wave energy, the motions, emissions, and powering requirements of ships operating in adverse weather conditions can be significantly...

Supervisory Team: Chris-Kriton Skylaris (90%) Andrea Russell (10%)Project description:Proton-exchange Membrane (PEM) hydrogen fuel cells are an emerging technology for environmentally sustainable transport and other carbon-neutral energy applications. A crucial component of these devices are the metallic catalyst nanoparticles which allow the chemical...

Supervisory Team: Ioannis ZeimpekisProject description:Revolutionising the semiconductor industry with next generation 2D materials and devices.Moore's Law is currently being challenged with Nvidia CEO recently claiming it is over. The scaling of transistors cannot continue due to physical limitations of silicon posing a threat to the sustainable evolution...

Supervisory team: Neil SandhamProject descriptionYou will join a group of PhD students and post-doctoral researchers using high performance computing to advance understanding of high speed aerodynamics. Over the past decade we have developed efficient open-source software that enables us to run large numerical simulations with billions grid points on mixed...

Supervisory Team: Prof. Otto Muskens; Alberto PolitiProject Description:In this project, the student will develop new technologies for integrated quantum optical chips allowing programming and tuning of devices under different operating conditions and in particular for operation in a cryogenic environment. The ability to actively control different parts of...

Supervisory Team: Chris-Kriton Skylaris (80%) Jeremy Frey (20%) Project Description: The computational simulation of chemical reactions in materials requires an accurate, explicit description of their electrons. This can be achieved by quantum mechanical calculations from first principles, in particular with Density Functional Theory (DFT) which achieves a...

Supervisory Team: Professor Pedro Rivera and Dr Ben CameronProject description:Rail safety is dependent upon the ability to control the nucleation and growth of cracks. Current popular techniques focus on crack prevention, e.g. through grinding, but the mechanisms leading to failure remain largely ununderstood. The topic has recently been reviewed...

Supervisory Team: Jonathan GeorgePhD Supervisor: Jonathan GeorgeProject description:The School of Chemistry is offering a fully funded PhD studentship to a highly motivated candidate to start in September 2024. The student will carry out their doctoral research in the George Group, which has recently moved to the University of Southampton.BackgroundThe use...

Supervisory team: Ben LinetonProject descriptionThe mechanical response of the cochlea to sound exhibits an intriguing array of different non-linear phenomena, involving interactions across time and frequency. These remain poorly understood but can be assessed using otoacoustic emissions (OAEs): low-level sounds detectable in the ear canal.OAEs are measured...

Supervisory Team: Dr Christine Evers Project Description: Are you keen on conducting research at the intersection of artificial intelligence, deep learning and robot perception? We are recruiting a fully-funded (UK fees) PhD student who will work amongst a team of researchers on an exciting, EPSRC-funded research programme on "Active Audition for Robots...

Supervisory Team: Professor Gill Reid & Dr Richard Knoghton Project Description:Developing new chelate scaffolds for binding radiofluorine and radiometals – towards combined theragnostic agents for imaging and therapy in medicine Applications are invited from suitably qualified and motivated candidates for an EPSRC CASE PhD studentship based in Chemistry...

Supervisory Team: Dr Adrian Nightingale, Dr Amber Annett, Dr Blair Thornton, Dr Rand Ismaeel Project descriptionAutonomous underwater vehicles (AUVs) are becoming increasingly widespread in ocean science as sensor platforms that can measure the oceans with minimal human input and maximum efficiency (and hence reduced carbon footprint). Furthermore, they can...

PhD Supervisor: Thomas BlumensathSupervisory Team: Thomas Blumensath (ISVR), Daniel Clark (ECS), Mark Mavrogordato (Engineering)Project descriptionX-ray computed tomography uses X-ray radiation to generate three dimensional images of an object's external and internal structure. The method is not only used for medical diagnostics but is also increasingly used...