Research Scientist/Senior Research Scientist

3 weeks ago


Tranent, East Lothian, United Kingdom Charles River Laboratories - Scotland Full time
At Charles River, we are passionate about improving the quality of people's lives. When you join our global family, you will help create healthier lives for millions of patients and their families.

Charles River employees are innovative thinkers, who are dedicated to continuous learning and improvement. We will empower you with the resources you need to grow and develop in your career.


As a Charles River employee, you will be part of an industry-leading, customer-focused company at the forefront of drug development.

Your skills will play a key role in bringing life-saving therapies to market faster through simpler, quicker, and more digitalized processes.

Whether you are in lab operations, finance, IT, sales, or another area, when you work at Charles River, you will be the difference every day for patients across the globe.

Job Summary

The Chromatographic Bioanalysis department is a large team located at our site in Tranent, East Lothian.

We are looking for a Research Scientist to join the method development team within the department, to participate in the development of quantitative assays on our fleet of over 20 high spec LC MS instruments.


As a CRO we have the opportunity to work with a large variety of analytes, from small polar molecules to peptides, proteins, nanoparticles and oligonucleotides.

This broad range of analytes and our involvement in a large variety of programme designs, from early-stage pre-clinical investigative work to in-vitro biosimilar evaluation and clinical trials, means that we are always expanding our knowledge and skills.

As well as our ever-evolving workflow, our consistent involvement with the industry through conferences, literature, and multi-company project teams, provide additional opportunities for development of both the industry and individuals.


In this role you will act as a scientific expert, as well as planning and organizing for the efficient development of bioanalytical methods.

This will involve using a variety of analytical techniques, or undertaking original research to develop new techniques, to establish methods suitable for generating data in a regulatory environment in a timely and cost-effective manner.


In more detail the role will include:

  • Responsibility for the development of LC conditions, optimizing MS/MS parameters and refining extraction procedures for the quantitative analysis of analytes from biological matrices. Including responsibility for decision making based on the data generated.
  • Routinely communicating effectively with internal and external stakeholders regarding study organization, progress, and challenges.
  • Leading complex troubleshooting, both during method development studies and in collaboration with other teams during later stages of an assay's usage
  • Contribution to the generation of scientific papers and presentations
  • Proactively mentoring junior method development scientists, to promote talent development.
  • Demonstrating innovation through development of alternative scientific approaches and improvement of existing processes.
Job Qualifications

Applicants should have:

  • A minimum of a BSc or equivalent in a scientific analytical related discipline.
  • Familiarity with the use of standard laboratory equipment and analytical instrumentation.
  • Experience developing assays in an analytical laboratory, preferably in a bioanalytical department.
  • An understanding of appropriate regulatory guidance in bioanalytical method validation in addition to current GLP/GCP regulations
  • Excellent communication (verbal and written), presentation and interpersonal skills.
  • Effective decision-making skills and the ability to work independently in a fast-paced environment.
  • A proven level of problem-solving ability and adaptability, in relation to both scientific and project management challenges.
  • Experience supervising and developing junior colleagues.
  • A proven ability to identify, design and conduct research projects based on analysis of industry trends.
This role is closing Wednesday, 19 June 24.

Due to high volume of applications we are receiving if you have not heard anything from Charles River Laboratories Edinburgh regarding the next steps of our recruitment process within 3 weeks of the closing date then please conclude you have been unsuccessful.

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance.

From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.

Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO).

We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.

Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities.

Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges.

Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people's lives.

Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe.

We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.

For more information, please visit

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Research Scientist, Pharmaceutical, Quantitative Analyst, Senior Scientist, Science, Research, Data
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