Molecular Histology

Site Name: UK - Hertfordshire - Stevenage

Posted Date: Apr 3 2023

At our world class scientific hub Hertfordshire, UK, our Histology department operating as an integral part of the global Bioimaging platform currently has an exciting career opportunity for a talented Molecular Histologist with a passion for science, multi-discipline integration, and applying their skill set to addressing human disease. We understand that the fewer barriers there are, the better our work can be. That is why we encourage an enterprising and highly collaborative approach to Discovery projects and Pre-Clinical programs.

We would be happy to consider candidates at a grade 8 or 7 level depending on experience.

In this role you will

• Successfully develop and implement single and multiplex immunohistochemistry /Immunofluorescence (IHC/IF), in situ hybridization (ISH) and dual IHC/ISH protocols on automated slide-based platforms, validate antibody clones and dilutions, antigen retrieval and signal amplification technologies to meet project timelines and requirements
• Support the use of digital whole slide scanning and application of advanced image analysis algorithms using commercially available platforms (e.g. HALO, Visiopharm)
• Work in partnership with project teams to understand project issues, provide input and report data to matrix teams, including close networking with all imaging groups across GSK. Apply broad knowledge of science, drug discovery and histology/ molecular assays to guide experimental designs that deliver the best possible science
• Work collaboratively with Discovery pathologists to identify project needs and develop tissue-based experiments to address project questions by agreed timelines
• Develop relationships with third parties for the purpose of outsourcing histology work packages when the need arises. Oversee quality control and all aspects of CRO out-sourced work packages
• Adopt and routinely apply other tissue-based assay technologies as they become embedded within the histology community
• Present data to represent Non-Clinical histology/Bioimaging in internal and external scientific seminars and publish scientific papers where appropriate
• Build molecular histology capability through development/training of members of the Non-Clinical histology team to support the nature and complexity of current and future Discovery requests
• Share responsibility for lab management, Human Biological Sample Management (HBSM), equipment maintenance, safety rep and similar roles

Closing Date for Applications: 17th April 2023 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact This will help us to understand any modifications we may need to make to support you throughout our selection process.

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• BSc/MSc or FIBMS. In Biomedical sciences, cellular pathology, biology, biochemistry or immunology
• Experienced FFPE and Cryo multi-species histology skill set
• Proven track record and expertise in Molecular Histology techniques; IHC, IF, ISH (manual and automated platform multi & duplex assays)
• Demonstrated Digital pathology expertise in tissue & cell-based Image analysis using commercially available platforms/software

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• MSc in Biomedical sciences, cellular pathology, biology, biochemistry or immunology
• Small animal necropsy skills

Why GSK?

Uniting science, technology and talent to get ahead of disease together

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Find out more:

Annual Report 2021

We're combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.

In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.

Find out more:

Our approach to R&D

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class(US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels

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