Head of Structural Biology STP

Found in: beBee jobs GB - 2 weeks ago

London, Greater London, United Kingdom Francis Crick Institute Full time

Reports to: Science Technology Platforms Director

This is a full-time and permanent position on Crick terms and conditions of employment.

This job advert will remain open to new applications until a suitable candidate has been identified. Please submit your application at the earliest availability to ensure its receipt.

Summary

The Crick organises access to high-end equipment and related technical expertise, for all its scientists, through our Science Technology Platforms (STP). Overall, there are 18 world-class STPs, ranging from cell services and biological research facilities, to high throughput screening, advanced sequencing and bioinformatics. These core facilities are crucial for the success of our research and represent a major investment by the Francis Crick Institute.

The Crick is looking to recruit an expert with an international reputation to lead and manage our world-leading Structural Biology STP. The Head of the Structural Biology STP will support research at the Francis Crick Institute by leading a multidisciplinary technology core facility which, in collaboration with Crick research groups, aims to describe and characterise the structure of individual proteins and protein complexes to help understand mechanisms behind human disease.

The STP currently employs 20 specialist staff. They provide specialised protein expression and purification, biophysics analysis and characterisation, and structure determination (x-Ray crystallography and Cryo-electron microscopy) to approximately 35 research groups.

The successful candidate will support a large and dynamic group of Crick researchers by fostering collaborations and providing scientific and technical support. They will coordinate and manage the different core facilities within the STP (protein expression and purification, biophysics, x-Ray crystallography and Cryo-electron microscopy) ensuring they work in a cohesive, collaborative and successful way, thereby contributing to high quality research, outputs and societal impacts.

Key responsibilities

These include but are not limited to:

  • Managing and leading a state-of-the-art Structural Biology core facility with cutting edge technology and a proactive approach to technology development.
  • Providing scientific expertise and leadership in performing and delivering an excellent and timely service to scientific users within the Crick.
  • Developing a long-term strategy for providing world class Structural Biology capabilities and to establish and supervise collaborative projects with Crick Research Group Leaders.
  • Supporting the development of the Cryo-electron microscopy facility to accommodate the increasing demand and complexity of research projects.
  • Participating in scientific discussions and brainstorming regarding experimental design, and new technological development and innovation in the different areas of structural biology (protein synthesis, biophysics, x-Ray crystallography and Cryo-electron microscopy), thereby ensuring the Platform remains at the leading edge to support scientific discovery.
  • Providing expertise and training to researchers and research support staff at the Crick and partner organisations.
  • Evaluating new techniques and instrumentation within the different fields in structural biology and implementing them into the STP when appropriate to maintain a cutting-edge facility.
  • Improving financial planning, compliance, and other administrative aspects of research projects.
  • Collaborating with other Crick researchers on long-range plans for innovative projects.
  • Maintaining continuing professional development as an active member of the scientific community by writing scientific articles, manuscripts, and reports for the research platform, as well as presenting research findings at scientific meetings and/or conferences.

Key experience and competencies

To be successful in this role you will have experience in leading a core facility of a similar nature and bring a clear vision and strategic approach to the development of the STP. You will embody and demonstrate our core Crick values: bold, open and collegial, in addition to the following qualifications, experience and competencies:

Essential

  • PhD (or equivalent experience level), in relevant scientific discipline (i.e. biophysics, crystallography, structural biology, biochemistry) and a strong track record in academic or industrial structural biology research
  • Extensive experience in research services
  • Broad evidence of excellence and recognition as a facility leader
  • Management experience in leading a facility or equivalent service unit
  • Ability to demonstrate senior management and leadership capability and skills
  • The candidate must demonstrate an open-minded approach to new directions and development in the life sciences
  • Ability to carry out goal-driven technological development projects while maintaining an excellent level of support to institute researchers
  • Excellent communication skills facilitating outreach to STP users and the ability to understand different user needs
  • Extensive experience of delivering output as part of collaborative projects
  • Significant expertise in Cryo-electron microscopy

  • Head of Structural Biology STP

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom The Francis Crick Institute Full time

    Location: The Francis Crick Institute, Midland Road, LondonSalary: Upwards of £73k, subject to skills and experienceShort summary The Crick organises access to high-end equipment and related technical expertise, for all its scientists, through our Science Technology Platforms (STP). Overall, there are 18 world-class STPs, ranging from cell services and...

  • Senior Laboratory Research Scientist

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom The Francis Crick Institute Full time

    Location: The Francis Crick Institute, Midland Road, LondonShort summary The post-holder will work in the Experimental Histopathology STP, providing advice, training, and expertise in a range of techniques to analyse cells and tissues from experimental models and human tissue.Experimental Histopathology (EHP) is a Science Technology Platform (STP) within the...

  • Senior Laboratory Research Scientist

    Found in: beBee jobs GB - 4 hours ago

    London, Greater London, United Kingdom The Francis Crick Institute Full time

    The Human Biology Facility (HBF) provides support and expertise to enable research utilising human materials and data, and to develop capability in core areas relating to stem cells, genetic modification and human model systems. We provide support to Crick researchers, including our growing number of clinical scientists, throughout the study lifecycle...

  • Head of Strings

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom Royal College of Music Full time

    Founded in 1882, The Royal College of Music (RCM) is a world leading music conservatoire with a prestigious history and contemporary outlook. Our excellence was recognised by the 2024 QS World University Rankings, in which we were ranked as the global top institution for both Music and Performing Arts by Subject.The RCM has a distinguished tradition of...

  • Laboratory Research Scientist

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom The Francis Crick Institute Full time

    Location: The Francis Crick Institute, Midland Road, LondonShort summary This is a core funded post within the Nervous System Development and Homeostasis Laboratory, headed by Dr Vassilis Pachnis and based at the Francis Crick Institute. The laboratory comprises a team of 9 scientists who use advanced molecular genetics and cell biological techniques to...

  • Postdoctoral Research Assistant

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom Queen Mary University of London Full time

    About the RoleApplications are invited for a Postdoctoral Research Assistant (PDRA) to work at the School of Biological and Behavioural Sciences (SBBS) in the research group of Dr. Mario dos Reis, as part of a BBSRC project on development of Bayesian methods to analyse large genomic datasets. We seek a highly motivated individual with relevant background in...

  • Associate Director, Derivatives Confirmations, Head of EMEA

    Found in: beBee jobs GB - 5 days ago

    London, Greater London, United Kingdom Royal Bank of Canada Full time

    Come Work with UsAt RBC, our culture is deeply supportive and rich in opportunity and reward. You will help our clients thrive and our communities prosper, empowered by a spirit of shared purpose.Whether you're helping clients find new opportunities, developing new technology, or providing expert advice to internal partners, you will be doing work that...

  • Postdoctoral Research Fellow

    Found in: beBee jobs GB - 3 days ago

    London, Greater London, United Kingdom UCL Full time

    About usThis is an exciting opportunity for an experienced scientist to join UCL as a Postdoctoral Research Fellow, working in the Laboratory for Molecular Cell Biology, a Division in the Faculty of Life Sciences, ranked No.2 in London and No.9 in the World for Life Sciences and Medicine (QS Rankings by Subject 2023).About the roleThe Acton Lab, funded by...

  • Head of Public Engagement

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom Courtauld Institute of Art, University of London Full time

    Job descriptionThe Courtauld is seeking to appoint a Head of Public Engagement to lead the Public Programmes department and work across the institution to develop further and oversee the delivery of an ambitious portfolio of programmes and an inspiring new public engagement strategy leading to our centenary in 2032. The Courtauld's Public Programmes...

  • Head of Partnership Development

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom University of Greenwich Full time

    The Head of Partnership Development & Engagement works closely with the Deputy Dean and Faculty Operating Officer as a member of the Faculty Management Team responsible for leading, with the PVC and Deputy Dean, the Faculty's enterprise, and Engagement strategy both in the UK and internationally. This will include developing and implementing initiatives to...

  • Head of Partnership Development

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom UNIVERSITY OF GREENWICH Full time

    Faculty of Education, Health and Human SciencesLocation: Avery Hill CampusSalary: £56,021 to £64,914 plus £4069 London weighting per annumContract Type: PermanentClosing Date: Sunday 28 April 2024Interview Date: Friday 10 May 2024Reference: 4509The Head of Partnership Development & Engagement works closely with the Deputy Dean and Faculty Operating...

  • Head of Data Governance

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom Mackenzie Jones IT Full time

    Head of Data Governance - Data Governance Lead. £900 Day Rate - Outside IR35. 12 Month Contract. Hybrid Working - 2/3 days onsite. London. T6/MN/18647. *Applicants must be eligible to work in the UK Our global client is seeking to secure a Head of Data Governance - Data Governance Lead. The role will lead a Data Governance team delivering on a SAP S/4 Hana...

  • Postdoctoral Researcher in Skeletal Disease

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom The Royal Veterinary College, University of London Full time

    Location: Camden (King's Cross, London)Closing Date: 23.59 hours BST on Sunday 28 April 2024Interview Date: Friday 03 May 2024A postdoctoral research associate with expertise and interest in skeletal biology and/or immunology is sought to study the mechanism of pathological bone formation and resorption in ankylosing spondylitis (AS). The successful...

  • Head of Girls PE

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom Twyford Church of England High School Full time

    We are looking for a Head of Girls PE in a school which offers comprehensive CPD, exciting development opportunities and good promotion prospects for our teachers. The main purpose of this post is to achieve outstanding outcomes at KS3/4 in the curriculum and wider curricular offer within the sports department. We offer the following seasonal sports within...

  • Human Tissue Governance Manager

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom The Francis Crick Institute Full time

    Job Description & Person SpecificationSummaryThe Human Tissue Governance Manager will be a key member of the Human Research Governance Team, working closely with both operation teams and with science colleagues at all levels. The team is the central point of contact for all matters relating to research involving human materials or data. It leads on our...

  • Head of Catering

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom London School of Economics and Political Science Full time

    LSE is committed to building a diverse, equitable and truly inclusive universitySalary from £59,670 to £69,092 pa inclusive with potential to progress to £76,562 pa inclusive of London allowanceAn exciting opportunity has arisen for Head of Catering at LSE. Catering services is an important part of the student and staff experience at LSE, with a turnover...

  • Postdoctoral Research Assistant

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom Queen Mary University of London Full time

    About the RoleWe are seeking a postdoctoral research assistant to join the group of Dr Mirjana Efremova in the Centre for Genomics and Computational Biology, to work on a CRUK funded project to investigate the role of cell plasticity in metastasis in colorectal cancer. Our lab is focused on understanding the cellular and molecular mechanisms underlying cell...

  • Research Assistant

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom London School of Hygiene & Tropical Medicine Full time

    The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world's leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.We are seeking to...

  • Head of Enterprise Architecture

    Found in: beBee jobs GB - 2 weeks ago

    London, Greater London, United Kingdom Queen Mary University of London Full time

    About the Role As the Head of Enterprise Architecture, you'll be the linchpin in developing a coherent and strategic IT framework that propels our client towards achieving its ambitious objectives. Your role is instrumental in nurturing a culture of transparency, efficiency, and innovation within the IT organisation, ensuring their technology investments...

  • Head of Tax

    Found in: beBee jobs GB - 1 week ago

    London, Greater London, United Kingdom EuroLUX Consulting Full time

    We have a Head of Tax Compliance services role working at a senior level managing a portfolio of clients, leading the Tax services team across the UKAny additional information you require for this job can be found in the below text Make sure to read thoroughly, then apply.It's a role in a company with a progressive structure, and scope to make a successful...