Clinical Research Fellow in Paediatric RHeumatology

2 weeks ago


Liverpool, Liverpool, United Kingdom University of Liverpool Full time
We are seeking an enthusiastic and motivated individual to conduct research for a discreet project

  • NEPHROTARGET: looking at Exploring Treat to
  • Target (T2T) and Urine Biomarker Monitoring in Lupus Nephritis Affecting Children and Young People.


This research aims to enhance the T2T approach for Childhood-onset Systemic Lupus Erythematosus (cSLE) by incorporating innovative urine biomarker monitoring, as cSLE patients have a high risk of renal failure and mortality.

T2T approaches have shown success in reducing disease activity and serious complications in a number of conditions and are advocated in cSLE.

However, it remains uncertain whether current 'T2T targets¿ adequately capture lupus nephritis (LN) activity and treatment response.

To enhance the accuracy of this approach for LN, we aim to incorporate the measurement of a urine biomarker panel alongside the T2T approach.


Funded by the Alder Hey Children¿s Kidney Fund, this role offers a unique blend of clinical and research responsibilities with the aim of improving outcomes for young Lupus Nephritis (LN) patients.


The post holder would undertake the post full-time (part time options available on request), with the post holder returning to full-time clinical training after the project ends.

You will have excellent attention to detail, with effective communication skills and a flexible approach to work.

You should have a MBChB or equivalent, and have completed FY1, FY2 and ST1 of paediatric training.

This post is available for from 1 September 2024 until 28 February 2025.

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