Clinical Scientist-associate Director

1 week ago

Abingdon, Oxfordshire, United Kingdom Adaptimmune Full time

Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company's unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors. Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.

About the Team:
Clinical Development Operations (CDO) lead the delivery of innovative, high-quality clinical development trials at Adaptimmune. In CDO we are committed to making cell therapy a viable option for all eligible patients. We are a highly effective, innovative and fast-moving team that's open to change and new ideas.

We work through a culture of cross-functional collaboration to deliver our clinical trials to plan, achieving high quality in everything we do.

Everyone in CDO leads by example, where people are inspired to be the best they can be, being curious about new ways of working and being data-driven in decision-making.


MUST RESIDE IN THE SURROUNDING AREA, COMMUTABLE TO THE MILTON PARK SITE

PRIMARY RESPONSIBILITY
The Associate Director level Clinical Scientist role is a global role, based in either the US or the UK.

The role provides scientific input and oversight, as well as leadership and management of cross-functional execution of clinical studies, within Adaptimmune's programs.


The Clinical Scientist will be responsible for global clinical trial delivery including the planning, management and reporting of trials in accordance with company plans/objectives, GCP, local country requirements and company standard operating procedures.

This includes writing and/or reviewing protocols, interacting with sites for feasibility assessment, site selection, start up, study conduct, data cleaning, data review, and study close-out, for one or more clinical trials.


KEY RESPONSIBILITIES

  • Support study design, translate scientific imperative into operational delivery of trials. Review and/or writing of study concept, protocol, study plans, IP management plans, CSRs.
  • Lead the crossfunctional Study Conduct Team drive operational delivery and facilitate issue resolution.
  • Plan timelines, conduct study feasibility, risk assessment/management and contingency planning. Ensure timelines are communicated to all personnel assigned to the study (including vendors)
  • Plan and/or conduct site evaluation and initiation; develop and maintain effective relationships with clinical sites globally.
  • Provide guidance on protocol and procedures in the development of eCRF design.
  • Review monitoring visit reports: liaise with monitors to understand any trends on data management issues/ICF issues/study binder issues/site staff issue to develop solutions.
  • Review clinical trial data monitor data quality and ensure appropriate quality measures are in place.
  • Ensure consistency of study execution across studies to facilitate data analysis and regulatory filing.
  • Study specific vendor interaction and coordination
  • Maintain TMF and ensure inspection readiness.
  • Proactive stakeholder management and communication of progress and issues

QUALIFICATIONS & EXPERIENCE

Required

  • Minimum of a BA/BS in Life Sciences Degree
  • Previous leadership in a matrix environment
  • 7+ years of industrysponsored clinical trial management experience required. Experience with biologics or cell and gene therapy is a plus.
  • Strong knowledge of clinical operations and the regulatory process experience independently running/managing multiple clinical trials preferably within the oncology area
  • EDC including trial management, data review, issuing and resolving queries, CRF design/review/ approval.
  • Prior experience with clinical protocol development and/or regulatory submissions and management
c8kSikZ5wV

  • Clinical Trial Support Specialist

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Adaptimmune Full time

    Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company's unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors.Our company...

  • Associate Director

    1 week ago

    Abingdon, Oxfordshire, United Kingdom M3USA Full time

    medeConnect Healthcare Insight is the full-service market research team within M3 (EU) Ltd. The primary function of the team is to design research programmes to meet our clients' business objectives and provide impactful, actionable findings. We expect that for the first 6-9 months in role the successful candidate will focus almost exclusively on project...

  • Associate Director, Market Research

    1 week ago

    Abingdon, Oxfordshire, United Kingdom M3EU Full time

    Company DescriptionAbout M3:Founded in 2000, with start-up investment capital from Sony, M3's mission is to make use of the internet to increase, as much as possible, the number of people who can live longer and healthier lives, and to reduce, as much as possible, the amount of unnecessary medical costs. Key achievements of M3 Inc.include: Named in Fortune's...

  • Associate Director, Global Regulatory Affairs

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Adaptimmune Full time

    Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company's unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors.Our company...

  • Principal Scientist I, Bioanalytical Sciences

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    Job Details: Principal Scientist I, Bioanalytical Sciences Full details of the job. Vacancy Name Vacancy Name Principal Scientist I, Bioanalytical Sciences Vacancy No Vacancy No VN391 Employment Type Employment Type Permanent Location of role Location of role Abingdon About the Company About the Company Immunocore (NASDAQ: IMCR) is a pioneering,...

  • Associate Director, Regulatory Operations

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Adaptimmune Therapeutics PLC Full time

    Adaptimmune is a fully integrated cell therapy company, designed and built from the ground up with four U.K.- and U.S.-based biotechnology hub locations. Our comprehensive capabilities and teams include preclinical research, clinical development, translational sciences, autologous and allogeneic manufacturing, and in-house commercial and corporate...

  • Associate Director

    1 week ago

    Abingdon, Oxfordshire, United Kingdom RPS Group Full time

    RPS is looking for an Associate Director to join us in our specialist EIA team, to be based at either Abingdon, Manchester or Edinburgh. We are working on some of the most exciting Nationally Significant Infrastructure Projects in the UK and internationally, including large scale energy projects - think GW rather than MW This includes solar, offshore wind,...

  • Associate Director

    1 week ago

    Abingdon, Oxfordshire, United Kingdom RPS Group Full time

    RPS is looking for an Associate Director to join us in our specialist EIA team, to be based at either Abingdon, Manchester or Edinburgh. We are working on some of the most exciting Nationally Significant Infrastructure Projects in the UK and internationally, including large scale energy projects – think GW rather than MW This includes solar, offshore...

  • Senior Research Scientist II

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    Job Details: Senior Research Scientist II – Oncology Research, Functional Pharmacology Full details of the job. Vacancy Name Vacancy Name Senior Research Scientist II – Oncology Research, Functional Pharmacology Vacancy No Vacancy No VN454 Employment Type Employment Type Full Time Location of role Location of role Abingdon, UK About the Company...

  • Associate Dentist

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Rodericks Dental Partners Full time

    Role DescriptionBe one of the first applicants, read the complete overview of the role below, then send your application for consideration.Associate DentistWootton Dental Centre, 4 Besselsleigh Road, Abingdon, Oxford, OX13 6DNClinical Manageron-site parkingCo-Funding OpportunitiesEmbark on a new career journey with Wooton dental, a practice located in a...

  • Director Customer Operations

    4 weeks ago

    Abingdon, Oxfordshire, United Kingdom Abbott Laboratories Full time

    About AbbottAbbott is a global healthcare leader, creating breakthrough science to improve people's health. We're always looking towards the future, anticipating changes in medical science and technology.The Opportunity Abbott Rapid Diagnostics is part of Abbott's Diagnostics family of businesses, bringing together exceptional teams of experts and industry...

  • Director Customer Operations

    1 month ago

    Abingdon, Oxfordshire, United Kingdom Abbott Laboratories Full time

    About AbbottAbbott is a global healthcare leader, creating breakthrough science to improve people's health. We're always looking towards the future, anticipating changes in medical science and technology.The Opportunity Abbott Rapid Diagnostics is part of Abbott's Diagnostics family of businesses, bringing together exceptional teams of experts and industry...

  • Scientific Director- Medical

    1 week ago

    Abingdon, Oxfordshire, United Kingdom BioLegend, Inc. Full time

    This is a fixed term maternity cover of circa 12-13 months. The Scientific and Government Affairs role is responsible for driving the scientific narrative of the Revvity Infectious Diseases Diagnostics (IDx) business unit and the Revvity IDx range of products, and for ensuring scientific integrity throughout product development and commercialisation. The...

  • Director of Financial Operations

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Redefined Ltd Full time

    Closing date for applications: Friday 24th of May 2024 This role is open to candidates based in the UK. You must have the right to live and work in the UK. This role will be hired on a hybrid basis, with at least 1 day per week worked from our office in either Milton Park, Oxfordshire (OX14) or 240 Blackfriars, London, and the rest of your time worked...

  • Director, Scientific and Government Affairs

    1 week ago

    Abingdon, Oxfordshire, United Kingdom BioLegend, Inc. Full time

    This is a fixed term maternity cover of circa 12-13 months. Job Summary The Scientific and Government Affairs role is responsible for driving the scientific narrative of the Revvity Infectious Diseases Diagnostics (IDx) business unit and the Revvity IDx range of products, and for ensuring scientific integrity throughout product development and...

  • QC Stability Scientist

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    About the Company Immunocore (NASDAQ:IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of...

  • Senior Research Scientist II

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    Immunocore (NASDAQ:IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech...

  • Management Board Member

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Ymca Of Central Maryland, Inc. Full time

    101 Walter Ward Blvd, Abingdon, MD 21009, USA Req #3217 Wednesday, June 5, 2024 Overwhelmingly, people who decide they want to be a part of the Y in Central Maryland tell us they do so because it reflects their values and a conscious decision, they've made about how they choose to live their lives. The happiest and most fulfilled Y associates are those who...

  • Facilities Manager Engineer

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    Full details of the job. Vacancy Name Vacancy Name Facilities Manager Engineer Vacancy No Vacancy No VN265 Employment Type Employment Type Permanent Location of role Location of role Abingdon About the Company About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to...

  • Laboratory Services Manager

    1 week ago

    Abingdon, Oxfordshire, United Kingdom Immunocore Full time

    Job Details: Laboratory Services Manager Full details of the job. Vacancy Name Vacancy Name Laboratory Services Manager Vacancy No Vacancy No VN433 Employment Type Employment Type Permanent Location of role Location of role Abingdon About the Company About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor...