Sequence Families Curator
4 weeks ago
About the team/job
The Sequence Families team, led by Alex Bateman, at the European Bioinformatics Institute (EMBL-EBI) is responsible for a number of world-leading protein family annotation resources, including Pfam and InterPro.
Pfam is a database of protein families, represented by multiple sequence alignments and profile hidden Markov models (HMMs). InterPro is a resource that classifies protein sequences into families, and predicts the presence of functionally important domains and sites. It does this by incorporating protein signatures from 13 different specialist international member databases, including Pfam. We are seeking a Biocurator to join the team on a full time basis working on the InterPro/Pfam project and contribute to the content of InterPro and Pfam databases.
Your role
Reporting to the Sequence Families Project leader you will be part of the Curation Team that maintains the InterPro and Pfam resources. You will have the opportunity to critically evaluate protein signature models for inclusion in new or existing InterPro entries, as well as write descriptive abstracts and assign GO term annotations.
You will also maintain and update Pfam database entries based on both user contributions and scientific literature, and take part in other curation activities, as needed. Some tasks may require the use of command line tools, basic scripts, and/or direct querying of relational databases. You will work closely with the rest of the curation and development team to ensure timely updates and releases of the various resources. You will also respond to user queries and requests, as appropriate.
Main duties and responsibilities:
You have
A degree in a biological or closely related scientific discipline, or equivalent experience in scientific data curation. Several years of experience in curating biological data, and/or experimentally investigating proteins. Experience with computational data entry and data standards. Experience in widely used bioinformatics tools related to protein sequence searching and alignment. is essential, using both GUI and command-line. Ability to read, digest, and summarize scientific literature. Basic/intermediate Linux/Unix commands. Have excellent communication skills, both written and oral. Attention to detail. Ability to constructively critique database entries and annotations generated by others. Able to manage time and meet deadlines. Good team playerYou might also have
A Ph.D. in a biological field would be advantageous but not essential. Experience using HMMER suite to build and search profile HMMs, is highly desirable. Demonstrated experience dealing with database helpdesks. Basic knowledge of querying relational databases, e.g., MySQL. Basic scripting knowledgeWhy join us
Do something meaningful
At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity.
Join a culture of innovation
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential.
Enjoy lots of benefits:
Flexible working arrangements Generous time off: 30 days annual leave per year, in addition to eight bank holidays Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) Benefits for non-UK residents: Visa exemptionWhat else you need to know
Contract Type: Supernumerary - This contract type will be required to pay National Insurance Contributions. Contract Duration: This position is a 12 month contract. International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants. Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities. EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here. Job location: This role is based in Hinxton, near Cambridge, UK. How to apply: To apply please submit a cover letter and a CV through our online system.-
Scientific Database Curator
5 months ago
Hinxton, United Kingdom European Molecular Biology Laboratory Full timeData Curation Hinxton, UK In this job Your role You have You might also have Why join us What else you need to know More about EMBL-EBI EMBL-EBI is a world-leader in archiving and disseminating 3D biomacromolecular and cellular structure data. The EMDB (ebi.ac.uk/emdb) and EMPIAR (ebi.ac.uk/empiar) teams play a key role in the dissemination of 3DEM data...
-
Computational Biologist
2 weeks ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeWe are seeking a talented Computational Biologist to contribute to the curation of genome assemblies at the Wellcome Sanger Institute. The successful candidate will be responsible for improving automated genome assemblies through manual curation using bespoke software and tools.About the Role:The Tree of Life project is generating genome assemblies for...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleThe Wellcome Sanger Institute is seeking a talented Computational Biologist to join the Genome Reference Informatics Team on a 2-year contract. As a key member of the team, you will be responsible for the improvement of automated genome assemblies through manual curation using bespoke software and tools.Key ResponsibilitiesManual curation of...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleThe Wellcome Sanger Institute is seeking a talented Computational Biologist to join the Genome Reference Informatics Team on a 2-year contract. As a key member of the team, you will be responsible for the improvement of automated genome assemblies through manual curation using bespoke software and tools.Key ResponsibilitiesManual curation of...
-
Computational Biologist
4 weeks ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
4 weeks ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
2 weeks ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute. The successful candidate will contribute to the curation of genome assemblies to produce high-quality chromosome-scale references.The Tree of Life project is generating genome assemblies for thousands of species. As a key member of...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a highly skilled Computational Biologist to join our Genome Reference Informatics Team at the Wellcome Sanger Institute. This is a 2-year contract opportunity that will involve enhancing genome assemblies to create top-notch chromosome-scale references.About the TeamThe Tree of Life project is dedicated to generating genome...
-
Computational Biologist
1 month ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a highly skilled Computational Biologist to join our Genome Reference Informatics Team at the Wellcome Sanger Institute. This is a 2-year contract opportunity that will involve enhancing genome assemblies to create top-notch chromosome-scale references.About the TeamThe Tree of Life project is dedicated to generating genome...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
1 month ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract. The successful candidate will contribute to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesImprove automated genome assemblies through...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
1 month ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract. The successful candidate will contribute to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesImprove automated genome assemblies through...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
2 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at Wellcome Sanger Institute on a 2-year contract contributing to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesThe improvement of automated genome assemblies through manual curation using...
-
Computational Biologist
3 weeks ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeAbout the RoleWe are seeking a talented Computational Biologist to join the Genome Reference Informatics Team at the Wellcome Sanger Institute. The successful candidate will contribute to the curation of genome assemblies to produce high-quality chromosome-scale references.Key ResponsibilitiesImprove automated genome assemblies through manual curation using...
-
Biocurator
5 months ago
Hinxton, United Kingdom EMBL-EBI Full timeWe are currently seeking a talented Biocurator to join the Human Genomics Team at the EMBL European Bioinformatics Institute (EMBL-EBI). The team provides genome variation and regulation resources as part of the Ensembl project, human variation interpretation services including the DECIPHER platform, and data portals for partners around the world. With...
-
Computer Biologist
5 months ago
Hinxton, United Kingdom Wellcome Sanger Institute Full timeDo you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges.We are seeking a talented Computational Biologist to join the Wellcome Sanger Institute on a 2 year contract contributing to the curation of genome...
-
Biocurator
1 month ago
Hinxton, United Kingdom EMBL-EBI Full timeBiocurator Job DescriptionWe are seeking a highly skilled Biocurator to join our Human Genomics Team at the EMBL European Bioinformatics Institute (EMBL-EBI). The team provides genome variation and regulation resources as part of the Ensembl project, human variation interpretation services including the DECIPHER platform, and data portals for partners around...
-
Biocurator
1 month ago
Hinxton, United Kingdom EMBL-EBI Full timeBiocurator Job DescriptionWe are seeking a highly skilled Biocurator to join our Human Genomics Team at the EMBL European Bioinformatics Institute (EMBL-EBI). The team provides genome variation and regulation resources as part of the Ensembl project, human variation interpretation services including the DECIPHER platform, and data portals for partners around...
