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Postdoctoral Research Associate

3 months ago

Edinburgh, United Kingdom The University of Edinburgh Full time

Full-time: 35 hours per week

Fixed-term:  (Sept 2024 – March 2027)

We are looking for a post-doctoral level molecular and cell biologist specialising in analysis of gene expression and investigating mutant phenotypes in Cryptococcus neoformans and Schizosaccharomyes pombe.

The Opportunity:

To conduct research and analysis pertaining to mechanisms of antifungal resistance via chromatin-mediated regulation in both Cryptococcus neoformans and Schizosaccharomyes pombe within the Allshire laboratory; contributing to the development of new ideas, approaches and concepts. To influence the overall direction and management of the research project and to contribute to publishing or otherwise disseminating the outputs of research.

Your skills and attributes for success: 

  • Ability to plan and execution specific elements of research projects, acting under general guidance from the PI.
  • Conduct growth, manipulation, and analysis of C. neoformans and S. pombe epigenetic regulation of gene expression using appropriate tools/conditions – developing/modifying tools/conditions when necessary. 
  • Implement RNA-seq, ChIP-seq and related protocols for analysis of histone PTM distribution and gene expression across the genome of wild-type, mutant and epimutant isolates.
  • Ability to collaborate and communicate with other researchers to improve experimental design, implement approaches and analyse data in order to expedite conversion of results obtained into publications.

£39,347 to £46,974 per annum

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