Senior Scientist
3 weeks ago
Senior Scientist - Molecular Virologist
Sussex, England
Permanent
£ Competitive salary and benefits
SRG are currently working very closely with a unique, growing biotechnology company committed to developing next generation vaccines with novel methods of delivery. Their ground-breaking technology is aimed at producing self-administered, thermally stable vaccines that can be widely distributed by mail. Due to continued expansion, they are looking to bring onboard a Senior Molecular Virologist who will be working with a small team of research scientists in a discovery setting. This is a very exciting opportunity to join an innovative biotechnology company and work with highly specialised, knowledgeable scientists at the forefront of discovery science.
Key responsibilities:
- Conduct experimental work aimed at growing and purifying viral vectors using a variety of mammalian tissue culture and virus purification techniques
- Investigate viral attributes and characterise wild-type viruses, both in vitro and in vivo, using a variety of virology techniques
- Develop novel bioassays aimed at testing the biological, immunological, and biochemical attributes of vaccine candidates
- Troubleshoot new assays and techniques, as needed
- Investigate host pathogen interactions and the immune mechanisms of protection induced by vaccines, using molecular virology research techniques
- Maintain awareness of developments in the field and be pro-active at introducing new techniques and capabilities into the team and wider organisation
- Prepare written reports and present data for audiences inside and outside the company
- Contribute to Analytical and Preclinical sections of CTA/IND submissions, Investigator Brochures, IMPDs, briefing packages for regulatory meetings
Key skills and experience:
- PhD in Virology, Microbiology, or related discipline and 2 years’ postdoctoral experience, or equivalent industrial experience.
- Strong understanding of viruses and viral infection. Experience working with animal/human viruses is essential.
- Excellent understanding of laboratory techniques for handling and working with viruses (including expansion in cell culture), acquired through working with pathogens or genetically modified viral vectors.
- Proven experience in developing assays in relevant virological, molecular, and serological techniques (i.e. virus propagation and titration, RT-qPCR, ELISA, serum neutralisation assays).
- Proven experience working with viruses in the areas of gene therapy, vaccine or anti-viral product development is desirable.
- It is desirable to have experience in the propagation and purification of viruses in the context of product development.
- Be an independent, creative, and highly skilful independent laboratory worker.
- Able to maintain a disciplined approach to research.
If you are interested in having a confidential discussion about this opportunity, then please reach out to me at paige.keenan@srgtalent.com
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