Research Scientist

4 weeks ago


Norwich, United Kingdom Earlham Institute Full time

The role:

This exciting position aims to develop novel bioinformatics pipelines that apply spatial transcriptomics approaches to investigate the genetic architecture of the clock at a single-cell resolution. These methods are at the forefront of cell genomics and will be deployed in both Arabidopsis and wheat.

As part of this position the post holder will:

Work collaboratively across the institute, together with researchers from the Iain Macaulay group.  Be involved in analysing existing datasets and working with the Plant Cell Atlas initiative. Analyse complex transcriptional datasets and collaborate with the Locke group at TSL, Cambridge to develop mathematical models describing the circadian clock. Have the opportunity to work within the cross-institute programme Delivering Sustainable Wheat on decoding regulatory sequences and understanding transcriptional networks. Have training in ML/AI approaches

Our ultimate aim is to use the clock as a model to investigate how complex regulatory networks work across multiple cell types and how cell state affects the clock. In addition to these roles, the post holder will have the opportunity to undertake co-supervision of PhD students within the group and develop management skills.

The ideal candidate:

We are looking for candidates with a PhD in computational or Plant Biology or closely related subject. 

They should have experience of applying computational biology and bioinformatics during their PhD studies, particularly to transcriptomic data analysis. It is important that this is evidenced in their application.

The ideal candidate will also be able to demonstrate experience of analysing single-cell RNA-seq data and should be a team player who enjoys working in a collaborative scientific environment. They should also have a broad knowledge of plant genomics, basic statistics, coding (expertise in R and/or python) and experience running bioinformatic workflows, potentially in an HPC environment. 

Experience of collaborating with other research groups and across disciplines would be advantageous. Whilst not essential, there will also be the opportunity for researchers to become involved with the experimental aspect of the project

Additional information:

Salary on appointment will be within the range £35,300 to £43,750 per annum depending on qualifications and experience. This is a full-time post for a contract of 36 months.

This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

The closing date for applications will be 20 June 2024.



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