Senior Research Technician

3 weeks ago


London, United Kingdom UCL Eastman Dental Institute Full time

About the role

We are seeking a Senior Research Technician to join the QSMND and be a part of the new United to End MND UK Partnership. United to End Motor Neuron Disease’s (U2EM; Phase 1) research strategy is to finalise human cell models of MND and identify novel disease biomarkers and therapeutic targets for this incurable condition. The work will focus on genetic engineering, gene expression modification, and treatments of cell models of MND to look at changes of cell viability and secretome.

You will be central in bridging observation from cell lines of the disease to translational approaches. You will optimise, maintain, and investigate human cell lines reproducing MND pathobiology, testing in vitro specific compounds and look at the cell response and biomarkers profile. You will work collaboratively with other team members and U2EM partners across the UK to exploit human MND cell models for the discovery of biomarkers and novel therapeutic targets.

The post is available immediately and funded by a grant from LifeArc until 30 June in the first instance.

If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team ().

Informal enquiries regarding the role can be addressed to Professor Andrea Malaspina ().

A full job description and person specification for this role can be accessed below.

About you

You’ll have an undergraduate degree in Neuroscience, Biology, or a related discipline, or equivalent research experience. Experience with iPSCs handling and genetic manipulation approaches is essential, as is experience with the development of immunoassays and homebrew assays, and use of single molecular array and MSD platforms. Excellent communication and interpersonal skills, strong problem-solving abilities, and the ability to act on your own initiative are also required for this role.

This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.

What we offer

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) Additional 5 days’ annual leave purchase scheme Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan Immigration loan Relocation scheme for certain posts On-Site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance

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