Clinical Scientist

3 weeks ago

Bristol, United Kingdom North Bristol NHS Trust Full time

Job summary

Clinical Scientist in Bioinformatics (Band 7)

Bristol Genetics Laboratory, South West Genomics Laboratory Hub

We are seeking a Clinical Scientist (Bioinformatics) to become an integral part of our Bioinformatics Team supporting our start-of-the-art diagnostic laboratory in delivering comprehensive genetic testing services to patients.

What we offer:

A chance to be at the forefront of precision medicine, contributing to life-changing diagnoses and therapies

An environment that values innovation, collaboration, and the professional growth of its team members

The opportunity to work with a diverse array of technologies and methodologies

We are supportive of flexible working and open to considering working from home options

To understand more about Pathology at North Bristol, click here to watch the video.

Main duties of the job

This is a varied and dynamic role, involving both the operation of in-service bioinformatics pipelines and contributing to the development of new bioinformatics services.

In-service duties will include running NGS pipelines for our Rare Disease and Cancer services, performing quality control checks and supporting with scientific queries.

The post holder will also collaborate with other members of the bioinformatics team to develop and validate new bioinformatics pipelines to support the delivery of the NHSE National Genomics Test Directory.

Other duties include contributing to staff training in bioinformatics and participating in quality assurance activities.

The post is open to HCPC registered Clinical Scientists in Bioinformatics. Applications from final year Scientist Training Programme (STP) trainees in Clinical Bioinformatics are welcomed.

The role demands a blend of specialist knowledge, analytical thinking and collaborative skills. Experience of working in a bioinformatics section of a diagnostic genetics laboratory service and knowledge of bioinformatic tools, resources and techniques applied to medical genetics are essential.

For candidates who are not yet registered, they will be expected to work towards HCPC registration and would be appointed on a salary band appropriate for their experience.

The successful candidate will be expected to work 37 1/2 hours per week full-time over seven days of the week. Part time and job share considered.

About us

As a new member of the Bristol Genetics Laboratory (BGL) Bioinformatics Team, you will be welcomed into a small, tight-knit group of professionals who have a passion for innovation and are committed to delivering high quality patient care.

We are a small team that values close relationships and mutual support, ensuring that every contribution is valued.

Our size allows for focused collaboration, where team members work closely together to achieve shared goals.

We are agile and responsive to change, quickly adapting to new challenges and embracing the latest advancements in bioinformatics with enthusiasm and expertise.

With a scientific and technical staff of over 100, BGL is housed in new state of the art Pathology laboratories in North Bristol NHS Trust.

BGL is a fully integrated Genomics Laboratory providing comprehensive Cancer and Rare Inherited Disease genomic testing to the South West with extensive specialist services attracting a large number of national and international referrals. BGL has a significant R&D programme and also benefits from co-location with the University of Bristol Learning and Research Centre in the Trust Science Quarter.

BGL is fully committed to the provision of high-quality training at all levels, as an accredited training centre.

Job description

Job responsibilities

Please refer to the Job Description for full details.

As a Clinical Scientist (Bioinformatics) key duties include:

Data Analysis & Interpretation : Conduct comprehensive analysis of genomic data using bioinformatics tools and methodologies. Interpret results in the context of rare diseases and cancer to support clinical decisions. Pipeline Development & Management : Develop, validate, and maintain bioinformatics pipelines for high-throughput genetic data processing. Ensure the accuracy and efficiency of data analysis. Service Development: Actively participate in the creation and enhancement of new genetic testing services. Stay abreast of advancements in the field of bioinformatics to drive innovation within the team. Training & Support : Assist with the provision of basic and specialised training in bioinformatics to various staff groups. Contribute to the training of trainees undertaking the Scientist Training Programme (STP). Assist in troubleshooting and optimising bioinformatics resources. Stakeholder Engagement : Build and maintain relationships with key stakeholders, including Clinical Scientists, Genetic Technologists, Informatics Scientists, research partners, and technology providers, to facilitate seamless service delivery. Quality Assurance : Take a proactive role in maintaining high quality standards to ensure maintenance of the laboratory UKAS accreditation status. Participate in internal audits, document control, and continuous improvement initiatives to uphold ISO standard 15189. Person Specification

Training

Essential

BSc (1st or 2nd class honours) in a Bioinformatics, Computer Science or Health Informatics discipline, or a relevant biological discipline with demonstrated abilities in bioinformatics and computing (first or second class) MSc, PhD degree or equivalent in a relevant subject

Desirable

HCPC registration in Clinical Bioinformatics or working towards registration

Work experience

Essential

Experience of working in a bioinformatics section of a diagnostic genetics laboratory service or similar Experience of developing and implementing bioinformatic tools and resources Experience of molecular genetics, diagnostic genomics services or similar

Desirable

Proven experience of successful project management Experience in IT, applications, developments, processes and organisation

Knowledge and skills

Essential

Knowledge of Next Generation Sequencing approaches and statistical techniques used in manipulation of large data analysis Knowledge of bioinformatic tools, resources and techniques applied to medical genetics Proven experience of working in UNIX/LINUX and BASH scripting Good programming skills in a modern object orientated scripting language (such as Python) suitable for pipeline development and ad hoc scripting Knowledge of SQL database design, development, and administration

Desirable

Programming skills in a language suitable for statistical analysis (for example R or Python) Experience using bioinformatics workflow languages (such as Nextflow or WDL) Experience in LINUX administration

  • Consultant Clinical Scientist

    1 month ago

    Bristol, United Kingdom UK Health Security Agency Full time

    Job summary Applications are invited for a full time consultant clinical scientist post, one of two new senior roles created to support the regional clinical virology service and contribute to the mission and strategic goals of UKHSA. This is an exciting opportunity to join our team of clinical virologists in a dynamic, innovative service, based at...

  • Consultant Clinical Scientist

    4 weeks ago

    Bristol, United Kingdom UK Health Security Agency Full time

    Job summary Applications are invited for a full time consultant clinical scientist post, one of two new senior roles created to support the regional clinical virology service and contribute to the mission and strategic goals of UKHSA. This is an exciting opportunity to join our team of clinical virologists in a dynamic, innovative service, based at...

  • Consultant Clinical Scientist

    1 month ago

    Bristol, United Kingdom UK Civil Service Full time

    Job summaryApplications are invited for a full time consultant clinical scientist post, one of two new senior roles created to support the regional clinical virology service and contribute to the mission and strategic goals of UKHSA. This is an exciting opportunity to join our team of clinical virologists in a dynamic, innovative service, based at UKHSA...

  • Principal Clinical Scientist

    1 week ago

    Bristol, Bristol, United Kingdom North Bristol NHS Trust Full time

    Principal Clinical Scientist in Rare Disease Genomics - AfC Band 8A An opportunity for a permanent 8A Clinical Scientist post has arisen in the Rare Disease Genomics service due to internal promotion. Bristol Genetics Laboratory (BGL) hosts a state-of-the-art Rare Disease Genomics service serving the South-West region for core genomics testing, with a...

  • Clinical Scientist in Cancer Genomics

    2 weeks ago

    Bristol, United Kingdom North Bristol NHS Trust Full time

    Job summary Bristol Genetics Laboratory - South West Genomic Laboratory Hub Southmead Hospital, Bristol Clinical Scientist in Cancer Genomics permanent posts available Open to HCPC registered Clinical Scientists and those approaching completion of the Clinical Scientist Training Programme. Appointment at Band 6 will be considered for...

  • Clinical Scientist

    1 week ago

    Bristol, Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust Full time

    Are you looking for a new, exciting role in paediatric audiology? Would you like to work in a friendly, forward thinking, high performing team? Do you want to work in a vibrant city?If yes, yes, and yes we are looking for an enthusiastic professional who is passionate about paediatric audiology. The role is based within the paediatric audiology team at...

  • Clinical Scientist

    2 weeks ago

    Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) Full time

    Job summary An exciting opportunity has arisen for an enthusiastic individual to join our large, dynamic and friendly team of audiologists, clinical scientists, apprentices and trainees in the Adult Audiology service across several sites in Bristol & Weston. We offer a broad range of services including diagnostic audiovestibular assessment (DAV) and...

  • Principal Clinical Scientist

    1 month ago

    Bristol, United Kingdom UK Civil Service Full time

    Job summaryThe UKHSA Mycology Reference Laboratory in Bristol is one of the few reference laboratories that are situated outside the main reference facility currently at Colindale. The laboratory undertakes local diagnostic testing and national reference and referred tests across a varied panel, together these currently amount to more than 65,000 tests per...

  • Clinical Scientist

    4 weeks ago

    Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust Full time

    Are you looking for a new, exciting role in paediatric audiology? If yes, yes, and yes we are looking for an enthusiastic professional who is passionate about paediatric audiology. The role is based within the paediatric audiology team at Children's Hearing Centre (CHC). The team consists of assistant audiologists, paediatric audiologists, and...

  • Director - Clinical Science

    1 month ago

    Bristol, United Kingdom Barrington James Full time

    Company Overview: We are a leading biopharmaceutical company dedicated to advancing the field of cell metabolism and developing innovative therapies across oncology and inflammation. Our mission is to transform patient care through the discovery and development of groundbreaking treatments that target key pathways of the immune system. Position Summary: ...

  • Director - Clinical Science

    1 week ago

    Bristol, Bristol, United Kingdom Barrington James Full time

    Company Overview: We are a leading biopharmaceutical company dedicated to advancing the field of cell metabolism and developing innovative therapies across oncology and inflammation. Our mission is to transform patient care through the discovery and development of groundbreaking treatments that target key pathways of the immune system. Position Summary: ...

  • Gmp Production Scientist

    2 weeks ago

    Bristol, United Kingdom Hyper Recruitment Solutions Ltd Full time

    We are currently looking for a GMP Production Scientist to join a brand new Cell and Gene Therapy GMP facility in the Bristol area. As the GMP Production Scientist you will be responsible for carrying out GMP production activities for a varied range ofATMP clinical products. This is a great opportunity to work on a wide range of client projects in a rapidly...

  • Protein Engineer

    2 months ago

    Bristol, United Kingdom Hlx Life Sciences Full time

    Job Description: We are working in partnership with a start-up biotech firm, supporting them in the growth of their scientific team. They're actively seeking Protein Engineers with Phage Display expertise across varying levels of seniority to join their team. This role is full-time and requires on-site presence for five days a week. Role Summary: In...

  • Casual Vascular Scientist

    3 weeks ago

    Bristol, United Kingdom GP Care UK Limited Full time

    Job summary We are looking for a vascular scientist to join our team of sonographers and vascular scientists across Bristol, North Somerset, South Gloucestershire, Gloucestershire, and Swindon on a casual basis. We are a flexible employer with a position available for casual hours. However, if you are looking for more regular hours then, please do...

  • Clinical Scientist

    1 month ago

    Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) Full time

    Job summary Are you looking for a new, exciting role in paediatric audiology? Would you like to work in a friendly, forward thinking, high performing team? Do you want to work in a vibrant city? If yes, yes, and yes we are looking for an enthusiastic professional who is passionate about paediatric audiology. The role is based within the...

  • Clinical Scientist

    4 weeks ago

    Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) Full time

    Job summary Are you looking for a new, exciting role in paediatric audiology? Would you like to work in a friendly, forward thinking, high performing team? Do you want to work in a vibrant city? If yes, yes, and yes we are looking for an enthusiastic professional who is passionate about paediatric audiology. The role is based within the...

  • Clinical Scientist

    4 weeks ago

    Bristol, United Kingdom University Hospitals Bristol and Weston NHS Foundation Trust Full time

    Are you looking for a new, exciting role in paediatric audiology? Would you like to work in a friendly, forward thinking, high performing team? Do you want to work in a vibrant city? If yes, yes, and yes we are looking for an enthusiastic professional who is passionate about paediatric audiology. The role is based within the paediatric audiology...

  • Research Scientist

    1 month ago

    Bristol, United Kingdom Neuronostics Limited Full time

    Applications will be considered on a rolling basis from 16/05/2024 until the post is filled.  Are you seeking a career with purpose? Do you want to make a difference to the lives of millions of people? Then join Neuronostics Award-winning and rapidly growing, our mission is to enable fast and accurate diagnosis and treatment for everyone with a suspected...

  • Research Scientist

    4 weeks ago

    Bristol, United Kingdom Neuronostics Limited Full time

    Applications will be considered on a rolling basis from 16/05/2024 until the post is filled.  Are you seeking a career with purpose? Do you want to make a difference to the lives of millions of people? Then join Neuronostics Award-winning and rapidly growing, our mission is to enable fast and accurate diagnosis and treatment for everyone with a suspected...

  • Research Scientist

    1 month ago

    Bristol, Bristol, United Kingdom Neuronostics Limited Full time

    Applications will be considered on a rolling basis from 16/05/2024 until the post is filled. Are you seeking a career with purpose?Do you want to make a difference to the lives of millions of people?Then join NeuronosticsAward-winning and rapidly growing, our mission is to enable fast and accurate diagnosis and treatment for everyone with a suspected...