Data Scientist Biologics Engineering Oncology RD

3 weeks ago


Cambridge, United Kingdom Lifelancer Full time

BUSINESSAREA

Join the BiologicsEngineering team at AstraZeneca where we are responsible for thediscovery and optimisation of nextgeneration biological drugcandidates across all key therapy areas. We are developing inhousebiologics discovery platforms and novel drug modalities to addressunmet medical needs. Be empowered to act fast on smart risks andkeep ahead in the fastpaced Oncologyfield.

What youlldo

You will work closely with ourRD scientists in fields of software engineering lab automationcomputational modelling and machine learning with access tobiologics RD data across AstraZeneca constantly generating new datato both build and inform predictive models. This role provides theopportunity for a motivated Bioinformatician / Data Scientist todevelop and manage the flow of data to create endtoend datamanagement capabilities that will have a significant impact on thedelivery of the novel biologics drugs of thefuture.

  • Work withscientists across Biologics Engineering to develop endtoend datamanagement capabilities for biologics discovery creating automatedpipelines for the flow of data.
  • Developapplications to configure and customize commercial GenedataBiologics software for tracking biologics discovery data fromantibody screening protein engineering and proteinproduction.
  • Extend the functionality ofGenedata Biologics by developing custom computational tools usingits Java Software Development Kit for data ingestion from labinstruments and for data analysis.
  • Collaboratewith IT functions responsible for the deployment and maintenance ofthe live Genedata Biologics system and its integration withexternal databases.
  • Collaborate with webapplication developers to integrate the Genedata Biologics systemwith custom applications for experiment design and dataanalysis.
  • Collaborate with machine learningcolleagues to develop an active learning system that continuallytrains machine learning models on data from biologics experimentsand uses these data to inform subsequent experiments.
  • Learn about leading machine learning methods forbiologics design and for active learning applied to biologicsexperiments.

Essentialfor the role

  • MScdegree or equivalent experience in computer science bioinformaticsor in a relevant computational field
  • Experience of working in a scientific environmentgenerating insights from RD data sets preferably DrugDiscovery.
  • Experience with SQL includingconfiguring and querying databases programmatically.
  • Experience developing highquality object orientedsoftware in Java or Python.
  • Experience withsoftware development best practices.
  • Experience working with Genedata Biologics or similarplatform for biological data management.
  • Experience working within a team environment.
  • Cando attitude. Acts with integrity and does the rightthing. Desire to learn andgrow.

Desirable for therole

  • Ph.D. in relevantfield
  • Experience working at interface of dry /wet lab. Knowledge of data formats for lab automationequipment.
  • Demonstrated agile methodologyfamiliarity
  • Experience developing debuggingand data analysis pipelines and an understanding of the datarequirements for downstream machine learning.
  • Exposure to graph database systems and related querylanguages e.g.SPARQL

Please use thebelow link for job application and quickerresponse.


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