Scientist – Early Respiratory

6 months ago

London, United Kingdom AstraZeneca Full time

R-203168: Associate Principal Scientist - Early Respiratory & Immunology

Imperial College, London

Competitive Salary & Excellent Benefits

Introduction to role:

Join us at AstraZeneca in the Early R&I (Respiratory and Immunology) department, where our bold ambition is to achieve early intervention, durable remission, disease modification and cure of chronic diseases. We are recruiting world-class scientists who are passionate about the possibilities of science to change lives

We are seeking highly motivated senior researchers with a strong understanding of neuronal reflexes and respiratory disease, to join our Bioscience team within the Early R&I department based at Imperial College, London.

What you’ll do

In this role you will focus your research on characterising mechanisms driving neuronal reflexes in airway and immunological disease. You will be a key member of the team and undertake the design and execution of bioscience and experiments. You will also work closely with key leaders in other team and in partner functions to ensure project goals are met. You will be responsible for preparing, reviewing and reporting scientific activities, including keeping accurate records. The role will sometimes involve implementing protocols over timelines that extend outside of normal working patterns.

Essential Skills/Experience:

A PhD or equivalent, in a relevant scientific discipline with 5+ years postdoctoral/industrial experience. Experience in extracellular electrophysiological recording techniques in airway sensory nerves. Knowledge of and experience in afferent single fibre techniques. Possess an understanding of key biological pathways in respiratory diseases such as asthma, COPD and IPF. Current PIL license holder with extensive experience in the planning and execution of in vivo studies especially in respect to the 3Rs. Experience with working with human biological samples with knowledge of appropriate regulations. Experience of cellular imaging and recording techniques in primary cells. Demonstrable experience in the identification, establishment and implementation of new technologies and methods. Substantial publication record and experience in presenting at scientific meetings. Proven experience in training, supervision and mentoring. Highly organised and self-motivated, with the ability to work independently as well as collaboratively within a team.

Desirable Skills/Experience:

Possess an understanding of key biological pathways in immunological disease. Strong understanding and technical skills in multiple biochemical and molecular techniques including primary cell culture, quantification of mRNA (qPCR), protein expression, ELISA, Western blot, etc.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office / lab. But that doesn't mean we're not flexible. We balance the expectation of being in the office / lab while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca?

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Join us if you want to continuously learn and try new things. This is the place to build a meaningful career as we push the boundaries of science to deliver life-changing medicines. We are always listening and learning from people who live with the diseases our medicines treat. It enables us to better understand their needs and, ultimately, diagnose and design the right treatments to impact patients' lives.

Next Steps

This advert will be running from Monday, 24th June 2024, and we welcome your application as soon as possible. The scheduled closing date is Friday, 28th June 2024.

Where can I find out more?

This is what we’re made of: Our sustainability ambition: Recent Publications:

Date Posted

24-Jun-2024

Closing Date

28-Jun-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

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