Research Associate
4 weeks ago
Fixed-term: The funds for this post are available until 28 February 2026 in the first instance.
Applications are invited for a Postdoctoral Research Associate (PDRA) position towork on the development and applications of a microfluidic platform foranalysing protein aggregation, with a focus on developing and further improving the optical technology used for detection, a project funded by the Michael J. Fox Foundation. The PDRA will work in the group of Professor Tuomas Knowles in the Yusuf Hamied Department of Chemistry at the University of Cambridge.
The aim of this interdisciplinary project is to develop an approach for detecting biomarkers that allow early diagnosis of Parkinson's disease, provide a means to track disease progression, and support the development of future therapeutics. A particularly attractive route to achieve this objective is to directly measure the seeding activity of misfolded and aggregated forms of the central protein driving Parkinson's disease (PD), alpha-synuclein. Yet, the ability to measure and quantify the seeding activity of pathological aggregates in clinical samples has remained elusive. Here, we propose to address this challenge by developing a quantitative and practical seeding assay in digital format which allows better quantification. Success with this project will open a platform and path towards quantitative PD biomarker detection.
The project aims to develop a novel toolbox enabling the digital quantification of single aggregates supporting PD diagnosis and following disease progression. To this end, the PDRA will combine optical detection with fluorescence microscopy and microfluidic techniques to develop a biophysical toolkit that allows real-time characterisation of alpha-synuclein aggregation at a single aggregate resolution. The PDRA should have a relevant specialist area in optics, including single-molecule confocal and fluorescence microscopy, along with designing and engineering of purpose-specific optical setups. Prior experience with image recognition algorithms and microfluidics is an advantage but not required.
Applicants will be expected to work collaboratively in an interdisciplinary environment, interact and communicate effectively with a team of scientists with a wide range of expertise in biophysics and physical chemistry.
Appointment at the Research Associate level is dependent on the award of a PhD. Those who have submitted but not yet received their PhD will be appointed at the Research Assistant level, which will be amended to Research Associate once the award of the PhD has been confirmed.
The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
-
Cambridge, United Kingdom University of Cambridge Full timeWe wish to recruit a Research Associate / Senior Research Associates in the Department of Engineering, to work on the EPSRC programme grant "Transforming networks - building an intelligent optical infrastructure (TRANSNET)". Optical networks underpin the global digital communications infrastructure, and the next-generation digital infrastructure needs more...
-
Research Assistant
4 weeks ago
Cambridge, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available for 2 years or until the Grant end date (30th April 2026), whichever is earliest. A position exists for a Research Assistant/Associate working in the Department of Physics, connected to the Accelerate Programme for Scientific Discovery. The Accelerate Programme for Scientific Discovery is a high-profile...
-
Research Associate
4 weeks ago
Cambridge, United Kingdom Reed Scientific Full timeReed Scientific are currently recruiting for a research associate to join an internationally renowned Cambridge biotech. Role: Research Associate Location: Cambridge Hours: Full-time, Monday - Friday Contract: Permanent **Salary**: Competitive Essential Qualifications: MSc and 2 years of practical lab experience Essential Skills: extensive experience with...
-
Research Associate
5 days ago
Cambridge, United Kingdom Science Solutions Recruitment Ltd Full timeA Cambridge-based biotechnology company is seeking a Research Associate with experience in the optimisation and development of immunoassays to join their Translational Biology team, supporting PK and PD studies for their impressive pipeline of novel immune-oncologytherapeutics. As a Research Associate you will: - Assist in the development and optimisation...
-
Senior Research Associate/Research Associate
1 week ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeTwo posts are available within Tim Dalgleish's research programme at the MRC Cognition and Brain Sciences Unit, a Postdoctoral Research Associate (PDRA) and a Senior Research Associate/PDRA. The post holder will be a member of the clinical research programme run by Tim Dalgleish who will line manage the post holder. The post holder will work on a Wellcome...
-
Research Associate
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeThe Hebrew Studies section of the Department of Middle Eastern Studies at the University of Cambridge invites applications for a Postdoctoral Research Associate in the field of modern reading traditions of the Hebrew Bible.One of the major projects in the Hebrew Studies section is the compilation of a reference grammar of Biblical Hebrew. The new grammar...
-
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeWe are looking for a Research Associate/Senior Research Associate to join the Raspberry Pi Computing Education Research Centre in the Department of Computer Science and Technology.The Research Associate/Senior Research Associate will play a pivotal role in conducting and leading research projects focused on computing education within the school system in the...
-
Research Assistant/Research Associate
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeThe Sawarkar lab at the MRC Toxicology Unit is looking to appoint a Research Associate (Postdoctoral Fellow) to contribute to its programme on Epigenetics, tRNA transcription and Neurodegeneration. The project will use state-of-the-art genomic technologies to identify epigenetic determinants that lead to protein misfolding in neurons. Using single-cell...
-
Research Assistant/research Associate
1 day ago
Cambridge, United Kingdom University of Cambridge Full timeWe are looking for a statistical geneticist to join the Cardiovascular Epidemiology Unit (CEU), Department of Public Health and Primary Care at University of Cambridge. The post holder will work with Dr Xilin Jiang and Professor Michael Inouye while collaborating with Professor Alkes Price (Harvard TH Chan School of Public Health) and senior scientists at...
-
Research Assistant/research Associate
4 weeks ago
Cambridge, United Kingdom University of Cambridge Full timeWe are looking for a statistical geneticist to join the Cardiovascular Epidemiology Unit (CEU), Department of Public Health and Primary Care at University of Cambridge. The post holder will work with Dr Xilin Jiang and Professor Michael Inouye while collaborating with Professor Alkes Price (Harvard TH Chan School of Public Health) and senior scientists at...
-
Research Assistant/research Associate
5 days ago
Cambridge, United Kingdom University of Cambridge Full timeWhere the successful applicant does not yet have a PhD, they will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that they will be appointed as a Research Associate upon successful completion of their PhD). The salary for a Research Assistant is £29,605- £33,966, the salary for a Research Associate is...
-
Cambridge, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available for 2 years in the first instance. Applications are invited for a 2-year Postdoctoral Research Associate (PDRA) under the supervision of Prof Erwin Reisner (Yusuf Hamied Department of Chemistry at the University of Cambridge) and Dr Bart de Nijs (Cavendish Laboratory Physics Department at the University of...
-
Research Associate
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available until 28 February 2026 in the first instance.Applications are invited for a Postdoctoral Research Associate (PDRA) position to work on the development and applications of a microfluidic platform for analysing protein aggregation, with a focus on developing and further improving the optical technology used for...
-
Research Associate
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available until 28 February 2026 in the first instance.Applications are invited for a Postdoctoral Research Associate (PDRA) position to work on the development and applications of a microfluidic platform for analysing protein aggregation, with a focus on developing cutting-edge microfluidic techniques for...
-
Research Assistant
4 weeks ago
Cambridge, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available until 30 September 2025 in the first instance. A position exists for Research Assistant/Associate in Quantum Materials research. Position Description: The Cavendish Laboratory's Quantum Matter group is looking to appoint a postdoctoral researcher to investigate electronic and magnetic states in...
-
Research Associate
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full timeFixed-term: The funds for this post are available until 28 February 2026 in the first instance.Applications are invited for a Postdoctoral Research Associate (PDRA) position to work on the development and applications of a microfluidic platform for analysing protein aggregation, with a focus on high-throughput data analysis and management, a project funded...
-
Research Associate in Ultrafast Vibrational
1 week ago
Cambridge, United Kingdom University of Cambridge Full timeAppointment at research associate is dependent on having a PhD (or equivalent experience), including those who have submitted but not yet received their PhD (in which case appointment will initially be made at research assistant and amended to research associate when the PhD is awarded). The research assistant salary (grade 5) falls within the range £28,929...
-
Research Associate
4 weeks ago
Cambridge, United Kingdom The One Group Full timeThis unique role for a **Research Associate** will combine your strong technical research experience with grant writing. Based in facilities belonging to Cambridge University and also with some travel to research facilities in Pisa, Italy, you will have a lead role in the technical development of this ground-breaking work, which is bringing Graphene and...
-
Research Assistant/research Associate
4 weeks ago
Cambridge, United Kingdom University of Cambridge Full timeThe Sawarkar lab at the MRC Toxicology Unit is looking to appoint a Research Associate (Postdoctoral Fellow) to contribute to its programme on Epigenetics, tRNA transcription and Neurodegeneration. The project will use state-of-the-art genomic technologies to identify epigenetic determinants that lead to protein misfolding in neurons. Using single-cell...
-
Research Assistant/Research Associate
2 weeks ago
Cambridge, United Kingdom University of Cambridge Full timeThe Sawarkar lab at the MRC Toxicology Unit is looking to appoint a Research Associate (Postdoctoral Fellow) to contribute to its programme on Epigenetics, tRNA transcription and Neurodegeneration. The project will use state-of-the-art genomic technologies to identify epigenetic determinants that lead to protein misfolding in neurons. Using single-cell...
