Associate Principal Scientist, Biophysics

5 days ago

Hoddesdon, United Kingdom Pharmaron Full time

Associate Principal Scientist, Biophysics

As an Associate Principal Scientist, you will leverage your expertise in Biophysics to independently execute and deliver on multiple projects. You will work collaboratively with multidisciplinary teams, demonstrating strong problem-solving abilities and excellent organizational skills. This is a rewarding opportunity for a biophysicist who is passionate about tackling challenging and innovative projects while maintaining high standards of quality and professionalism.

At Pharmaron, we offer:

Vibrant and dynamic employment –  we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting  Opportunities to develop your skills and yourself –  our rapid growth brings greater opportunities for you to learn and grow faster A great team where we all support each other –  enjoy your work – after all you spend about a third of your time here 

Key roles and responsibilities:

To support biology projects by working independently to plan, execute and deliver on project goals.  Demonstrate competency in the core laboratory skills required to support biology assay development, validation and screening. Such skills include, but are not limited to, routine use of core instrumentation and laboratory techniques, guided use of higher end laboratory techniques and instrumentation, and an understanding how their work influences drug discovery.   Execute experiments, interpret results, and be able to plan and recommend next steps and/or additional experiments in a timely manner to solve scientific issues. Where appropriate the individual will seek guidance (from a scientific supervisor / Line Manager) due to the level of complexity and/or the requirement for strategic input. Communicate with cross-functional teams to ensure that scientific work is appropriately reported via laboratory notebooks and presentations both internally and externally to the client. Document and report results of all experiments in a manner consistent with department practices and governing procedures, as applicable. Document and report results of all experiments in a manner consistent with department practices and governing policies.

Requirements:

Ph.D. in Biochemistry, Biophysics or a related field with at least 5 years of relevant work experience in Drug Discovery setting, or an M.S./B.S. with 10 years of relevant industrial work experience  Hands on experience with Surface Plasmon Resonance (SPR) and other biophysical techniques such as Microscale Thermophoresis (MST), Isothermal Titration Calorimetry (ITC) and Differential Scanning Fluorimetry (DSF) applied to study various modalities including protein-protein interactions and protein-small molecule interactions, RNA-small molecule, degraders, molecular glues etc.  Experienced leading biophysics-related scientific projects, responsible for generating, analysis and presenting complex biophysical data while maintaining client satisfaction and delivery on project objectives  Candidates with strong background and experience running FP, FRET, kinetic FRET assays or Mass Spectroscopy with relevant knowledge in Drug Discovery field will also be considered Excellent communication skills and ability to present rationale, key data, issues and accomplishments to other members of the scientific team and clients Good fit with Pharmaron culture and values of highly collaborative, team-oriented research with great organisation skills and attention to details Able to apply a dynamic and flexible approach towards achieving client-based objectives and meeting challenging deadlines as required

About Pharmaron

Come and  join a cutting-edge company that tackles the toughest scientific challenges for the world’s leading pharmaceutical companies.

At our company, we are passionate about advancing science and delivering solutions for our clients. We operate with ethics, integrity and professionalism. We work as a team and empower our employees to reach their full potential.

Our Hoddesdon campus in Hertfordshire is a hub of innovation and excellence. It has over 5,000m2 of premier R&D space, including state-of-the-art GMP facilities for API, formulation and process chemistry. Our Analytical Chemistry team provides vital support to our chemistry functions and science partners with advanced analytical solutions. We have recently expanded our capacity with a new laboratory containing 40 fume hoods. We are looking for an Associate Principal Scientist with expertise in Analytical Chemistry to join our growing team. 

We offer a competitive salary and a progressive and comprehensive suite of employee benefits We offer state of the art working environment in our modern Hoddesdon site We offer the opportunity for growth and development and will support funding for relevant training and development programmes 

Why Should You Apply?

This is an opportunity for you as an expert in Biophysics to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department. Build and shape your career in an environment that sets and commits to the highest standards of Chemistry. To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.

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