Research Nurse

Found in: Talent UK C2 - 2 weeks ago


London, United Kingdom Imperial College London Full time

We are seeking a committed and enthusiastic Research Nurse to support a novel and innovative study investigating beta-blocker symptoms in heart failure, to inform patients’ decision making and improve patient care.

The study (ENABLE-HF: pErsonalised Nocebo Assessment of Beta-blockEr symptoms in Heart Failure) has been awarded a prestigious project grant by the British Heart Foundation. We will study people who previously tried taking beta-blocker tablets for heart failure, but stopped them because of symptoms that they and/or their doctor thought were due to the tablets. These people are currently missing out on the life-prolonging benefit of beta-blockers.

In this study we will develop, for the first time, an individualised system to inform patients whether symptoms that stopped them taking beta-blockers are due to the beta-blocker itself or another reason such as heart failure, random chance, or the psychological expectation that they will have a side-effect (‘the nocebo effect’).

To find out this personalised information, each participant will go through an individual protocol consisting of weeks of taking beta-blocker tablets, blank (placebo) tablets, and no tablets. They will tell us how they feel every day using an app or by telephone. At the end, we will show them their personalised results so that they can decide whether to continue taking beta-blocker tablets.

This study is paramount in not only helping patients make an informed decision about their medications, but also in developing this protocol as a potential intervention to help patients with other chronic conditions take life-saving tablets. Accordingly, this post will be well-suited to individuals with interest/experience in heart failure, chronic disease management, psychology, tele-medicine and digital health.


You will join a dynamic and enthusiastic team of clinical researchers in heart failure, as part of a larger well-developed research group at the National Heart and Lung Institute at Imperial College London with a track record of publishing innovative and high impact studies. You will also have an honorary contract with our twinned NHS Trust (Imperial College Healthcare), which will be the primary clinical site for this study.

You will lead the day-to-day administration of the study. Typical duties include (but not limited to):

Identifying and screening potential participants.Conducting enrolment consultations including measuring blood pressure, heart rate, 12 lead ECG etc.Attending the weekly heart failure multi-disciplinary team meeting.Helping patients download and set up the study app on a smart-device.Retrieving data from the app server and managing the study database.Filling in data gaps by telephoning patients to get their daily symptom data.Staffing a telephone line for study queries from participants.General study administration including liaising with the drug/placebo provider, joint research office and other stakeholders.Attending meetings and complying with governance.Performing and reporting periodic study audit.Supporting manuscript preparation and presentation.

The successful candidate will receive training to perform the above activities. You will report to the clinical study lead (Dr. Sameer Zaman) who will provide day-to-day supervision, and the chief investigator (Dr. Graham Cole. Outside of the above activities, the successful candidate will receive personal mentorship from the study leads, including the opportunity for professional development and to get involved with a wide range of clinical and research activity being conducted in our unit.

The role will be based part-time: the successful candidate will provide cover 4 days a week (other patterns of working can be discussed), one of the study leads will provide cover on the remaining day. There is the possibility of a hybrid working model (in-person and remote), depending on the needs of the candidate and the study.


Applicants must be a qualified nurse with valid NMC registration and have experience of contributing to practice development and research in a clinical area.Knowledge of good clinical practice and proven clinical or management experience is desirable.Applicants should possess effective organisational and communication skillsHave the ability to work efficiently both independently and as part of a team.Candidates should be highly motivated, proactive, and ambitious,A stroNg background in and cardiovascular biology is desirablePrevious experience managing heart failure patients (acutely and/or in the community) is highly desirable.

This position is part-time (0.4-0.8 WTE) and fixed term (until August 2025 based at Hammersmith Campus in East Acton).


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