Senior Scientist
2 weeks ago
Title: Senior Scientist, Late-Stage Formulation Sciences
Location: The Discovery Centre, Cambridge, UK
Hybrid Working: 3 days on-site/ 2 days remote
Duration: 39 weeks
IR35 Determination: Inside
Business Area:
The Late-Stage Formulation Group is responsible for development of intended commercial formulations to advance AstraZeneca’s late-stage biologics portfolio, and the life cycle management of commercialized products. The group plays an integral part in the design and development of patient centric drug products.
Job Description/Position Summary:
Scientific position responsible for Late-Stage formulation development of biologic products. Design and execute formulation risk assessments and characterization studies and develop formulation control strategies for Drug Substance and Drug Product. Ensure robustness of intended commercial formulations, suitability for intended use of container closure/packaging systems, and in-use compatibility with clinical administration components. Exercise technical discretion and scientific rigor in experimental protocol design, data analysis, and results interpretation. Author marketing applications and support regulatory responses to approval. Develop new strategies and approaches to advance Late-Stage formulation development and deliver scientific and operational objectives.
Position Requirements/Skills and Abilities:
Knowledge of protein biochemistry and degradation mechanisms, biopharmaceutical manufacturing processes, combination drug products, and/or biophysical analytical methods is required. Hands-on experience with high-performance size exclusion chromatography (HPSEC), particle characterization and sizing (e.g. light obscuration), and aggregate characterization methods are strongly preferred. Experience with formulation and biopharmaceutical development, characterization, control strategy, quality risk management, and/or CMC regulatory guidance and filings is preferred. Skills leading, planning, and executing complex projects on tight timelines are important. High degree of self-motivation and drive for results are critical.
Education Requirements:
B.S. in chemistry, biochemistry, pharmaceutical sciences, engineering, applied sciences, or related field with a minimum of 8+ years of experience, M.S. with a minimum of 6+ years of experience, or Ph.D. with 0+ years of experience.
-
Senior Scientist
4 weeks ago
Cambridge, UK, Cambridgeshire, United Kingdom TechBio Talent Full timeSenior Scientist - Preclinical DevelopmentAn innovative biotech currently developing cutting edge biotherapeutics are looking to recruit an experienced scientist. This role will sit within the preclinical development team, working across their preclinical and clinical pipeline to enable continued development of products.The successful individual will play a...
-
Senior Scientist
1 week ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeJob Title: Senior ScientistJob Description:We are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will be responsible for leading the development of novel nanoparticle formulations for gene therapy applications.Key Responsibilities:Design and develop nanoparticles for drug...
-
Senior RNA Scientist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior RNA Scientist // Drug Delivery // Nanoparticle // CambridgeYou are a project leading RNA scientist with a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Our team is working with a rapidly growing biotech based in Cambridge that has developed unique polymer nanotechnology to encapsulate and release...
-
Senior Data Scientist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hyper Recruitment Solutions Full timeJob Title: Senior Data ScientistWe are seeking a highly skilled Senior Data Scientist to join our team at Hyper Recruitment Solutions. As a Senior Data Scientist, you will play a key role in driving the analysis and interpretation of complex biological datasets to support groundbreaking clinical trials and research initiatives.Key Responsibilities:1. Analyze...
-
Senior Data Scientist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hyper Recruitment Solutions Full timeJob Title: Senior Data ScientistWe are seeking a highly skilled Senior Data Scientist to join our team at Hyper Recruitment Solutions. As a Senior Data Scientist, you will play a key role in driving the analysis and interpretation of complex biological datasets to support groundbreaking clinical trials and research initiatives.Key Responsibilities:1. Analyze...
-
Senior RNA Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeUnlock the Potential of RNA TherapeuticsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs in Cambridge. As a project leading RNA scientist, you will have a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Our team is working with a rapidly growing...
-
Senior RNA Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeUnlock the Potential of RNA TherapeuticsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs in Cambridge. As a project leading RNA scientist, you will have a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Our team is working with a rapidly growing...
-
Senior Data Scientist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Kemioconsulting Full timeSenior Data ScientistKemioconsulting is seeking a highly skilled Senior Data Scientist to join their team. As a key member of the company, you will be responsible for analyzing large-scale biological data sets and developing novel statistical and machine learning methods.Key Responsibilities:Analyze large-scale biological data sets from in-house and publicly...
-
Senior Data Scientist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Kemioconsulting Full timeSenior Data ScientistKemioconsulting is seeking a highly skilled Senior Data Scientist to join their team. As a key member of the company, you will be responsible for analyzing large-scale biological data sets and developing novel statistical and machine learning methods.Key Responsibilities:Analyze large-scale biological data sets from in-house and publicly...
-
Senior Pharmacovigilance Scientist
1 month ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior Scientist - CNS Disease ModellingSingular is building brilliant biotechs, and we're looking for a Senior Scientist to lead our CNS disease modelling efforts.About the Role:We're working with a Cambridge-based start-up developing polymer nanoparticles for gene therapy drug delivery. As a Senior Scientist, you'll develop complex 'in-vitro' CNS disease...
-
Senior Pharmacovigilance Scientist
1 month ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior Scientist - CNS Translational ResearchWe are seeking a highly skilled Senior Scientist to lead our CNS translational research efforts. As a key member of our team, you will be responsible for developing complex 'in-vitro' CNS disease models to discover gene therapies.Our team is working with a Cambridge-based start-up that has announced a large...
-
Senior Pharmacovigilance Scientist
1 month ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior Scientist - CNS Translational ResearchWe are seeking a highly skilled Senior Scientist to lead our CNS translational research efforts. As a key member of our team, you will be responsible for developing complex 'in-vitro' CNS disease models to discover gene therapies.Our team is working with a Cambridge-based start-up that has announced a large...
-
Senior Pharmacovigilance Scientist
1 month ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior Scientist - CNS Disease ModellingSingular is building brilliant biotechs, and we're looking for a Senior Scientist to lead our CNS disease modelling efforts.About the Role:We're working with a Cambridge-based start-up developing polymer nanoparticles for gene therapy drug delivery. As a Senior Scientist, you'll develop complex 'in-vitro' CNS disease...
-
Senior Research Scientist
5 days ago
Cambridge, Cambridgeshire, United Kingdom Amazon Full timeAmazon is looking for a Senior Research Scientist to join our team and contribute to the development of innovative machine learning solutions.About the JobWe are seeking a highly skilled and experienced scientist with a strong background in machine learning and natural language processing to lead the development of new features and capabilities in our...
-
Senior Research Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior/Laboratory Research ScientistJob Summary:We are seeking an experienced Senior/Laboratory Research Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our research team, you will be responsible for leading the development of novel nanoparticle formulations for gene therapy applications.About the Role:As a...
-
Senior Research Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full timeSenior/Laboratory Research ScientistJob Summary:We are seeking an experienced Senior/Laboratory Research Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our research team, you will be responsible for leading the development of novel nanoparticle formulations for gene therapy applications.About the Role:As a...
-
Senior Data Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hyper Recruitment Solutions Full timeSenior Data ScientistWe are seeking a highly skilled Senior Data Scientist to join our team at Hyper Recruitment Solutions. As a Senior Data Scientist, you will play a key role in driving the analysis and interpretation of complex biological datasets to support groundbreaking clinical trials and research initiatives.Key Responsibilities:Analyse association...
-
Senior Data Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hyper Recruitment Solutions Full timeSenior Data ScientistWe are seeking a highly skilled Senior Data Scientist to join our team at Hyper Recruitment Solutions. As a Senior Data Scientist, you will play a key role in driving the analysis and interpretation of complex biological datasets to support groundbreaking clinical trials and research initiatives.Key Responsibilities:Analyse association...
-
Cambridge, Cambridgeshire, United Kingdom Bionow Full timeCK Group - Research Scientist / Senior ScientistJob Title: Research Scientist / Senior ScientistCategory: Technical rolesWe are seeking an experienced molecular biologist to join the Protein Engineering group at our research facility on Granta Park, Cambridge, UK.This is an exceptional opportunity to participate in pioneering science with an Industry-leading...
-
Senior Data Scientist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Kemioconsulting Full timeSenior Data ScientistKemioconsulting is seeking a highly skilled Senior Data Scientist to join their team. As a key member of the company, you will be responsible for analyzing large-scale biological data sets and developing novel statistical and machine learning methods.Key Responsibilities:Analyze large-scale biological data sets from in-house and publicly...
