Clinical Laboratory Scientist

4 hours ago

Manchester UK, Greater Manchester, United Kingdom Yourgene Health Full time

Job title: Laboratory Scientist (Genomic Services team)

Reports to: Laboratory Manager

Location: Manchester Science Park

Contract Type: Full-time, Permanent

Salary & Benefits: Competitive Salary + Benefits Package


About Yourgene Health:

Yourgene Health is a leading integrated technologies and services business, enabling the delivery of genomic medicine. The group works in partnership with global leaders in DNA technology to advance diagnostic science.


Yourgene primarily develops, manufactures, and commercialises simple and accurate molecular diagnostic solutions, for reproductive health, precision medicine and infectious diseases. The Group's flagship in vitro diagnostic products include non -invasive prenatal tests (NIPT) for Down's Syndrome and other genetic disorders, Cystic Fibrosis screening tests, invasive rapid aneuploidy tests and DPYD genotyping.


Yourgene has a range of innovative DNA sample preparation platforms, powered by Ranger® Technology, the Yourgene LightBench® and Yourgene QS250, ideal for cell free DNA applications in NIPT and oncology including liquid biopsy.


Yourgene also has a global laboratory service network equipped to be a full life-cycle partner for clinical, research and pharmaceutical organisations to support partners at the preclinical, clinical, and post market stage to develop, manufacture, obtain regulatory approval and commercialise new products and services. In addition, Yourgene offers and NIPT and high throughput Covid testing service.


Yourgene Health is headquartered in Manchester, UK with facilities in Taipei, Singapore, the US and Canada.


Our Culture:

Yourgene is a growing, vibrant and exciting place to work, we are looking for committed driven individuals to be part of our next growth journey. Our culture is described by our employee's as collegiate, friendly, professional, innovative, open and fast paced. We have nay social and well-being initiatives run by our Social Huddle that keep our sense of community alive during challenging times that the pandemic has thrown our way. At Yourgene we focus on putting values led programmes in place to ensure that we can attract, retain and develop our people. We want our people to have a career with Yourgene and we ensure that they are recognised and rewarded for their achievements and commitment, everyone plays a critical role in our growth journey.


Description of role:

Yourgene Health, part of the Novacyt Group, are recruiting for a Laboratory Scientist to join our genomic services team based at Manchester Science Park. The role of the Laboratory Scientist is to support high-quality and regulatory compliant Genomic Research, Clinical and Validation Services offered by Yourgene Genomic Services and to ensure that the laboratory environment is operating effectively and safely in accordance with instruction provided by the Laboratory Manager.


Key areas of responsibility:

Sample Processing

  • To contribute in providing a profitable routine scientific and applications service in line with the regulatory, quality and scientific expectations
  • To perform genomic services including; nucleic acid extraction, gene expression, SNP genotyping, copy number and structural variations, fragment analysis and methylation in accordance with written procedures
  • To liaise directly with the Laboratory Manager and/or Project Manager to ensure the schedule is executed in accordance with business needs
  • To ensure minimum stock levels of all reagents and consumables are maintained according to forecasts provided by the Laboratory Manager


Quality

  • To carry out all activities in accordance with the relevant quality standard
  • To ensure that all project folders and documentation are maintained appropriately in accordance with regulatory and business requirements
  • To review SOPs and technical documents as required
  • To liaise with the Quality Department and be familiar with the Quality Manual to ensure correct documentation and SOPs are in place and report non-conformances to ensure continual improvement. To comply with all health and safety and COSHH systems.


Process Improvement

  • To actively participate in process improvement programs
  • To perform as directed, method development and assay design in collaboration with internal and external Stakeholders
  • Actively interact with internal and external scientific community ensuring an up-to-date scientific knowledge in line with company strategy


Communication

  • To communicate effectively, professionally, and promptly so that all relevant information is forwarded to the appropriate personnel on a regular and timely basis
  • To participate in internal meetings, visits, and audits as and when appropriate and communicate any information back to the appropriate personnel


Troubleshooting

  • To effectively liaise internally with appropriate personnel and externally with Tech Support and Engineering Teams to provide technical support, resolve technical issues and carry out all associated troubleshooting activities as directed by the Laboratory Manager

Other

  • To undertake any other task that may be reasonably asked by the management which is consistent with the skill base or previous employment history of the employee


Education & Experience:

  • Minimum of a degree in a Science related subject (Biology, Biochemistry, Biotechnology, Molecular Biology, Genetics or similar) or experience of working in a science-related environment for 2 years.
  • Experience handling clinical samples for testing.
  • Experience performing clinical genomic and diagnostic testing using PCR and qPCR laboratory techniques.
  • Next Generation Sequencing (NGS) experience desirable, but not essential.
  • Knowledge and experience of nucleic acid extraction, gene expression, SNP genotyping, copy number and structural variations, fragment analysis and methylation in accordance with written procedures.
  • Experience working in an ISO 15189 accredited laboratory.
  • Experience using Q-Pulse or similar QMS.


Closing Date:

Sunday 12th January, 2025


Yourgene Health is committed to encouraging equality, diversity and inclusion among our workforce. The aim is for our workforce to be truly representative of all sections of society and for each employee to feel respected and able to give their best.

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