Aseptic Fill and Finish Biotechnologist

3 weeks ago

Oxford Oxfordshire Oxford Oxfordshire OX LT, Oxford, United Kingdom OXB Full time

Job description:

We want you to feel inspired every day. We’re future-focused and our business is growing. We succeed together through passion, commitment, and teamwork, and so can you.

We are currently recruiting for an Aseptic Filling Biotechnologist whose purpose is to primarily fill, inspect and pack Vector Products safely and assist, if required, in other OXB manufacturing facilities.

OXB’s Manufacturing Team is responsible for the production and aseptic fill and finish of vectors, for our clients and partners, to Good Manufacturing Practice (GMP) standard.

Your responsibilities in this role would be:

  • Ensuring that all work within the manufacturing facility is carried out in compliance with the facilities xx GMP procedures.
  • Provide OXB’s routine manufacture of vector product.
  • Execute production activities and requirements with other departments to achieve the production schedule, with minimal disruption to other activities within the facility
  • Assisting with Fill/Finish SOP's and batch documentation.
  • Perform core activities such as environmental monitoring, facility cleaning and clean transfer of materials in and out of the facility without supervision after training has been provided.
  • Be accountable as part of a team of aseptic filling biotechnologists working on shift pattern to successfully fill, inspect, label and pack Vector Product.
  • Completing Batch Manufacturing Records in a timely fashion throughout the manufacturing process.
  • Investigating quality incidents, deviations and improving procedures.
  • Working to high standards of health & safety

We are looking for:

  • BSc Life Sciences or equivalent or alternatively some previous experience of working within a biological or chemical GMP manufacturing environment
  • Basic understandings of aseptic fill and finish operations.
  • An understanding of GMP.
  • Good problem solving, interpersonal communication and team skills.
  • Excellent writing skills and computer literacy
  • Flexibility to work shift patterns inclusive of weekends.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

What’s in it for you:

  • Highly competitive total reward packages
  • Wellbeing programmes
  • Development opportunities
  • Welcoming, friendly, supportive colleagues
  • A diverse and inclusive working environment
  • Our values are: Responsible, Responsive, Resilient, Respect
  • State of the art laboratory and manufacturing facilities

We want you to feel inspired every day. We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and teamwork, and so can you.

Collaborate. Contribute. Change lives


We offer:

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.

Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).

Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.

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