Process Development Scientists

**Process and Development Scientist**

**Brussels, Belgium**

**Competitive Salary**

**Permanent Role**

We are working with a client who is a leading Contract Development & Manufacturing (CDMO) partner in Europe and the United States. They enable pharmaceutical and biotechnology companies to link their requirements for product success with their patients’healthier lives.

They are looking for a Process Development Scientist Downstream to join their department Process Development & Scale-Up (PDS), a higly motivated and dynamic team facing all day-to-day challenges and fun as ONE team. You will provide your expertise as a purificationexpert in the group’s global R&D activities. Next to R&D, you will supervise and provide support to the chemical lab technician in purification.

**What you'll do**:

- Analyze internal as well as external requests for new or existing projects, formulates proposals for the purification / isolation of products regarding costs, duration and deadlines definitions.
- Carry out / oversee the execution of laboratory tests:

- Feasibility study, development and optimization of purification / isolation processes for peptides and peptide derivatives - scale from milligram to hundreds of grams - taking into account the criteria of desired yields and purities. The aim is to developrobust and cost-effective purification / isolation processes suitable for transfer to production.
- Purification of crude peptides and peptide derivatives for process development projects up to PPQ
- Trouble-shooting for current productions
- Perform the necessary analyzes for the purification and isolation of products by the appropriate methods ((U) HPLC, LC / MS mainly)
- Maintain the laboratory equipments: preparative HPLC, lyophilizers, analytical HPLC
- Review the work performed by the purification lab technician from a quality point of view and/or compliance with the required procedures
- Participate in the drafting of batch files for purification / isolation processes
- Incorporates cGMP aspects into work (documentary aspects / lab notebooks)
- Interpret, synthesize and report the obtained results in a concise and clear manner, in the form of a report or PPT presentation in English
- Writes the required protocols / operating modes, quality procedures or work instructions necessary for the laboratory and verify their implementation

**Your Background**:

- Master in chemistry or equivalent by experience
- Ideally minimum of 3 years of experience in purification by preparative HPLC
- Experience in purification / isolation techniques (ion exchange, nanofiltration, atomization, lyophilization)
- Knowledge of peptide chemistry is a plus
- Experience in cGMP environment and CDMO is an asset
- Ability to work independently in a fast paced multitasking environment
- Excellent organization and coordination skills
- Strong customer oriented-mindset
- Flexible, able to set priorities and solution oriented
- Team spirit and ability to work in an interdisciplinary and international environment
- Strong oral & written communication skills (English & French) and cross functional collaboration skills

**What they offer**: The company offer a permanent contract, a competitive salary package and varied and motivating responsibilities.

On this occasion, LiCa Scientific is acting as an employment agency.