Research Associate
2 weeks ago
Job id: 099266. Salary: £44,105 - £48,878 per annum, including London Weighting Allowance.
Posted: 07 November 2024. Closing date: 05 December 2024.
Business unit: Natural, Mathematical & Engineering Sci. Department: Physics.
Location: Strand Campus. Category: Research.
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About us
The Faculty of Natural, Mathematical & Engineering Sciences (NMES) comprises Chemistry, Engineering, Informatics, Mathematics, and Physics - all departments highly rated in research activities and a wide-ranging portfolio of education programmes.
The study of Physics at King's dates back to the foundation of the College in 1829. The Department is currently undergoing significant growth with substantial investment in new appointments, research infrastructure and laboratory space refurbishment. We offer a range of UG courses in both three-year (BSc) and 4-year (MSci) versions as well as MSc and PhD programmes.
About the role
We are seeking to appoint a biophysicist or a cell/molecular biologist (preferably with a PhD in Physics, Cell/Molecular Biology, Chemistry, Biochemistry, Bioengineering or related disciplines) with proved experience in any area of mechanobiology.
This project aims to investigate the molecular mechanisms by which extracellular mechanical forces travel long distances inside the cell to reach the nucleus on biologically-relevant timescales, and how mechanical forces activate force-induced transcriptional programmes.
The project can be attacked from different perspectives (single molecule, single cell, or tissue level) but in all cases requires extensive experience in the relevant mechanical techniques, according to each relevant length-scale. The project is funded by the Leverhulme Trust. The project will be developed between the Francis Crick Institute and the Department of Physics at King’s College London
This is a full time post (35 Hours per week), and you will be offered an a fixed term contract until 31/12/25.
About you
Essential criteria
1. Hold a PhD in Biophysics, Physical Chemistry, Cell/Molecular Biology, Biochemistry, Bioengineering or equivalent
2. Extensive demonstrable experience with mechanobiology, although we are open to different length-scales (molecular, cellular, tissue) and with the mastering of the relevant related techniques.
3. Programming skills/quantitative approaches
4. Experience in student supervision, grant writing and project design
Desirable criteria
1. Experience in protein design, cloning, expression and purification
2. Experience in Cell Biology (Cell culture, transfections, CRISPR, etc.)
3. Experience with single molecule mechanics (AFM, magnetic tweezers, optical tweezers)
4. Experience with cell mechanics (AFM, Cell Magnetic tweezers, cyclic stretching, microfluidics, etc) experiments
5. Experience with confocal/spinning disk microscopy
Downloading a copy of our Job Description
Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “
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