Research Support Officer

**Open Date**
- 19/08/2024, 08:00

**Close Date**
- 16/09/2024, 23:55
- Research Institute- MRC Laboratory of Molecular Biology- Research Institute / Unit InformationThe MRC Laboratory of Molecular Biology (LMB) is one of the birthplaces of modern molecular biology and has played an important role in the development of many new techniques, most notably protein crystallography, cryo-electron microscopy, DNA sequencing and monoclonal antibodies. The LMB has a clear goal of understanding biological processes at the molecular level, with the ultimate aim of using this knowledge to tackle specific problems in human health and disease. We aim to tackle difficult, long-term problems, which often require investment over many years.

There are four scientific Divisions - Structural Studies, Protein and Nucleic Acid Chemistry, Cell Biology and Neurobiology. However, scientific collaboration between the different Divisions is extensive. Scientists are well supported by excellent scientific facilities and by the LMB Operations Group which maintains the core infrastructure and services of the institute.

The LMB provides an unsurpassed environment for both new and established researchers. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation
- Band- MRC - 4/5- Location- Cambridge- Salary- Band 5: £29,808 - £34,085 Band 4: £39,375 - £43,962- Contract Type- Fixed Term- Job Type- Science- Full Time / Part Time- Full Time- Contract Length- 2 Years- Job Description**_Band 5_**

**Overall purpose**:
To work within the group of Dr Kate McDole at the Laboratory of Molecular Biology (LMB), providing research support for a programme investigating the morphogenesis of the early mammalian embryo.

**Main duties/ Key responsibilities**:

- To assist with basic research by setting up, conducting and recording the outcome of experiments.
- To perform tasks arranged by your supervisor that may include some but not necessarily all of:

- Mouse colony husbandry and genotyping.
- Basic molecular biology to support the workflow for generating transgenic mice.
- Routine cell culture.
- Basic computational tasks.
- To organise and communicate information from the above tasks to your supervisor.
- To conduct literature and database searches.
- To contribute to the production of research reports.
- To ensure and maintain an efficient and tidy Laboratory.

Work with both your supervisor and other members of the project team on the above support tasks.

To ensure that all tasks are carried in accordance with good practice and in compliance with local polices and legal requirements.

To contribute to the smooth running of the research group, including the effective use of resources, working as part of a team, and responsible use of communal facilities.

**Working relationships**:
You will report to Dr Kate McDole. You will interact and collaborate with Postdoctoral Scientists, Research Support Staff and Students in your Group and LMB facilities.

**_
Band 4_**

**Overall purpose**:
To work within the group of Dr Kate McDole at the Laboratory of Molecular Biology (LMB), providing research support for a programme investigating the morphogenesis of the early mammalian embryo.

**Main duties/ Key responsibilities**:

- To assist with basic research by planning, setting up, conducting and recording the outcome of experiments.
- Basic analysis and interpretation of experimental results as appropriate.
- To perform a range of tasks and experiments as guided by your supervisor including:

- Mouse colony husbandry and genotyping.
- Manipulation, culture, imaging and analysis of early mammalian embryos.
- Molecular biology procedures required for the generation and analysis of transgenic mice.
- Cell culture assays (transfection, qPCR, microscopy, organoids or stem cell models).
- Basic computational tasks including use of image analysis software.
- To present information on research progress and outcomes as appropriate.
- To conduct literature and database searches.
- To contribute to the production of research reports and publications.
- To ensure and maintain an efficient and tidy Laboratory.

To plan and manage your experimental work within the project along with your supervisor and other members of the project team.

To contribute to the overall preparation of research for publication.

To ensure the research is carried in accordance with good practice and in compliance with local polices and legal requirements.

To contribute to the smooth running of the research group, including the effective use of resources, training of others and taking responsibility for use of communal facilities.

**Working relationships**:
You will report to Dr Kate McDole. You will interact and collaborate with Postdoctoral Scientists, Research Support Staff and Students, not only in your Group, but also other LMB groups, LMB facilities and with external Groups as nec