Allogenic Associate Scientist-gene Editing

7 days ago

Abingdon, United Kingdom Adaptimmune Full time

**Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company's unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors.**

**Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.**

Adaptimmune’s Off-the-Shelf T cell project is focused on the development of an iPSC derived T-cell product. The project team is growing rapidly to enable delivery of a ground-breaking new therapy and ensure the company’s position as a leader in the allogeneic cell therapy field. Gene editing is an integral part of the process and the gene editing team is expanding. An associate scientist is required to join the gene editing team to help support the following duties.
- Perform experiments based on established protocols and provide support to other staff in their experiments
- Maintain laboratory equipment and prepare reagents
- Maintain cell cultures and perform analytical testing of cells
- Genotyping of edited cells
- Support/prepare accurate records of experiments by use of electronic lab notebooks and reports
- Support/conduct data analysis, collation of results/data and communication of results/conclusions

Postholder will be working under the supervision of more senior scientists and will be able to develop further scientific skills to enable them to work more independently on routine experiments.

**Key Responsibilities**
- Conducting experiments and supporting colleagues, the group and Adaptimmune projects
- Participate in group and project meetings and discussions
- Routine lab maintenance

**Qualifications & Experience**
- Degree/MSc in Lifesciences
- Ability to learn and develop in order to work independently on non-routine experiments within a reasonable time frame
- Enthusiasm for technical challenges

**Desirable**
- Experience of laboratory work, cell culture practices and/or aseptic technique
- Experience with molecular biology techniques e.g. PCR, plasmid DNA purification.
- An understanding of gene editing including CRISPR-Cas9
- Familiarity with working to GxP and/or ISO 9001 standards

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