Research Associate

3 days ago


Sheffield, United Kingdom University of Sheffield Full time

An exciting position for a highly motivated postdoctoral research associate with experience of
mammalian gene expression technology is available to carry out research and development
underpinning commercial manufacture of commercial production of viral vectors for gene therapy.
This project is funded by the Cell and Gene Therapy Catapult (Guy’s Hospital, London), a centre of excellence in innovation, driving the growth of the cell and gene therapy industry. Together, we aim to mechanistically understand and improve AAV production by HEK cells in culture.

The post-holder will work in partnership with scientists at Sheffield and Cell and Gene Therapy
Catapult to improve production titre and quality of AAV produced by engineered HEK cells through engineering and isolation of HEK cell hosts with an improved AAV manufacturing capability. This is a fixed-term post for 18 months; the successful applicant will be working under the supervision of Professor David James and Dr Adam Brown at Sheffield in collaboration with Dr Maria Barreira and Dr Julie Kerby at the Cell and Gene Therapy Catapult.

We are looking for independent researchers who have demonstrated their ability to perform and
- If you are passionate about bioscience and next-generation therapies that transform the way that
disease is treated, then we would love to hear from you.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles whose talent and contributions
complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.


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