Principle Statistician Role

2 days ago

London, Greater London, United Kingdom Barrington James Full time £80,000 - £120,000 per year

Principal Statistician – Evidence Synthesis & HTA
Location:
Oxfordshire or London

Sector:
HEOR / Evidence Synthesis / HTA

Type:
Permanent, full-time

Our client is seeking a Principal Statistician to lead complex evidence-synthesis programmes and guide statistical strategy across high-impact HTA and market access projects. This role offers substantial influence, technical leadership, and the opportunity to shape methodologies within a collaborative, methodologically focused team.

The Role
As a Principal Statistician, you will own the design, delivery, and interpretation of statistical components across multiple evidence-synthesis and HTA projects. You will partner closely with multidisciplinary teams while providing direction and mentorship for developing statisticians.

Key Responsibilities Include

  • Designing statistical analysis plans and feasibility assessments for advanced evidence-synthesis challenges.
  • Coding and running analyses including pairwise meta-analysis, NMAs (including time-varying survival models), MAIC/PAIC, and individual patient data analyses.
  • Overseeing quality control processes to ensure methodological rigour and reproducibility.
  • Communicating complex statistical results clearly to clients and cross-functional teams.
  • Leading contributions to proposals, pitch presentations, and development of internal methodologies, SOPs, and QC frameworks.
  • Providing technical leadership, coaching, and mentorship to junior and mid-level statisticians.

About You
You bring depth of experience in evidence synthesis and thrive in roles that blend analytical excellence, leadership, and intellectual ownership. You enjoy shaping projects, influencing decision-making, and raising the statistical bar within a team.

Essential Experience

  • Master's degree or PhD in a quantitative discipline.
  • Significant experience leading evidence-synthesis statistical work (meta-analysis, NMA, indirect comparisons).
  • Proficiency in R, with familiarity in Bayesian approaches (e.g., BUGS).
  • Strong track record in HTA-focused analyses and interpreting results for health economic models and submissions.
  • Experience leading or mentoring statisticians and influencing analytical approaches.
  • Clear and confident communication of complex statistical concepts to diverse audiences.

Desirable

  • Experience with advanced NMA developments (e.g., ML-NMR).
  • Experience delivering training or statistical learning initiatives.
  • Consultancy experience managing multiple projects simultaneously.

What's On Offer
You'll join a supportive, engaging environment where quality, curiosity, and development are central. Expect:

  • A flexible working culture with genuine autonomy.
  • Regular interaction with senior leadership and the chance to shape internal methodologies.
  • Broad exposure across therapeutic areas and diverse HTA-focused projects.
  • The influence and visibility expected of a true Principal-level role.

  • Survey Statistician

    4 days ago

    London, Greater London, United Kingdom the National Centre for Social Research Full time £22,000 - £32,000

    Survey Statistician Department: Social SurveysEmployment Type: Full TimeLocation: London, UKCompensation: £22,000 - £32,000 / yearDescriptionWorking with other statisticians, contribute to the design of sampling and weighting schemes.Select survey samples using statistical software, with input from other statisticians (where required).Generate survey...

  • Trial Statistician

    7 days ago

    London, Greater London, United Kingdom The Institute Of Cancer Research Full time £38,891 - £52,324 per year

    Key InformationSalary: £38,891 - £46,804 OR £47,634 - £52,324 Commencement on the salary range is subject to comparable skills and experience.Duration of Contract: Fixed Term for 24 months.Hours per week: 35 hours per week (Full Time) / part time (miniumum 60% FTE) will be considered. Location: Sutton Closing Date: 23rd November 2025This role may be...

  • Principal Statistician

    6 days ago

    London, Greater London, United Kingdom Quanticate Full time £60,000 - £120,000 per year

    We are seeking an experienced Principal Statistician to join our growing team. The successful applicant will work as part of global teams, supporting pharmaceutical, biotechnology and medical device companies across many therapeutic areas. Quanticate values quality first, integrity, care, people, commitment to delivery, and inspiration. As such, employees...

  • Principal Statistician

    1 week ago

    London, Greater London, United Kingdom The Institute Of Cancer Research Full time £49,970 - £63,320 per year

    Key InformationSalary: £49,970 - £63,120 Commencement on the salary range is subject to comparable skills and experience. Duration of Contract: Fixed Term for 3 yearsHours per week: 35 hours per week (Full Time) / part time working (minimum 60% FTE) will be considered. Location: Sutton, SurreyClosing Date: 07th December 2025This role is eligible for ICR...

  • Principal Statistician

    2 weeks ago

    London, Greater London, United Kingdom Ipsen Full time £60,000 - £90,000 per year

    Title:Principal StatisticianCompany:Ipsen Innovation (SAS)About Ipsen:Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience. Supported by nearly 100 years of development experience, with global hubs in the U.S., France and the U.K, we tackle areas of...

  • Senior Statistician I

    2 weeks ago

    London, Greater London, United Kingdom Jobgether Full time £40,000 - £70,000 per year

    This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Senior Statistician I in the United Kingdom.In this role, you will contribute to the design, analysis, and reporting of clinical studies, supporting early-phase and ongoing trials. You will collaborate with cross-functional teams to deliver high-quality...

  • Technical Support

    2 weeks ago

    London, Greater London, United Kingdom Principle Full time £41,000 per year

    Application Support Engineer - Platform & ScriptingJob Title: Application Support EngineerLocation: Staines, Surrey - Hybrid, 2 days onsiteContract: 12-month PAYE | Inside IR35Paid on a weekly basis through us - Principle HR + Strong possibility of conversion to full-timeAnnual Salary: Up to £41,000 per annumStart Date: ASAPInterview Process: 2 rounds -...

  • Technical Program Manager

    2 weeks ago

    London, Greater London, United Kingdom Principle Full time £70,000 per year

    We're hiring an experienced Technical Program Manager to drive the delivery of complex, cross-functional software programs for a global technology leader developing next-generation virtual experiences.This is a hands-on, delivery-focused role for someone who's confident managing end-to-end technical programs, from definition to launch, across distributed...

  • Data Entry Statisticians | 2026

    2 weeks ago

    London, Greater London, United Kingdom Wimbledon Full time £148,000 per year

    Job DescriptionWe are looking to recruit a variety of people into data entry roles for Wimbledon 2026 working across our official venues: Qualifying Competition at Roehampton and The Championships at The All England Lawn Tennis Club.What are we looking for?Our values of Heritage, Integrity, Respect and Excellence are at the heart of everything we do. We are...

  • Research Associate

    2 weeks ago

    London, Greater London, United Kingdom King's College London Full time £40,000 - £60,000 per year

    About us: King's College London is one of the UK's leading research-intensive universities, with a strong commitment to excellence in education, research, and innovation. This post will be based in the Department of Psychology, within the School of Mental Health and Psychological Sciences at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN). The...