Senior Manager, Strategy, Portfolio and Operations

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

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About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

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Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):

• United States - Requisition Number: R-038110

• United Kingdom - Requisition Number: R-039602

• Netherlands, Belgium, Poland - R-039603

• Switzerland - Requisition Number: R-039604

Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.

Johnson & Johnson Innovative Medicine R&D is recruiting for a Senior Manager, Strategy, Portfolio and Operations.  This position is a hybrid role and will be located in High Wycombe, United Kingdom.

The Senior Manager, Strategy, Portfolio and Operations will be responsible for owning and executing end-to-end budget and headcount management, ensuring financial accuracy, strategic alignment, and operational excellence.  The individual will leverage advanced financial modeling and analytics to drive planning cycles, deliver insights, optimize resources, and support leadership with data-driven decision-making.

Principal Responsibilities:      

• Own end-to-end budget and headcount tracking, ensuring accuracy, timeliness, and alignment with strategic goals.

• Develop and maintain financial models to forecast spend, headcount trends, and scenario planning for investment decisions.

• Analyze budget variances and headcount shifts, providing actionable insights and recommendations to leadership.

• Drive strategic planning cycles, including annual budgeting, quarterly forecasting, and long-range financial planning.

• Partner with Finance, Human Resources (HR), and leaders to align headcount and budget strategies with organizational priorities.

• Monitor and report on portfolio health, including investment performance, run costs, and benefit realization metrics.

• Lead monthly and quarterly financial reviews, preparing executive-level dashboards and presentations.

• Ensure compliance with financial policies and controls, including audit readiness and documentation standards.

• Identify opportunities for cost optimization and resource reallocation, based on evolving business needs and technology landscape.

• Support workforce planning efforts, including tracking Full-Time Equivalents (FTEs), contractors, and open roles across initiatives.

• Design and implement Key Performance Indicators (KPIs) and metrics to measure financial efficiency, portfolio value, and headcount utilization.

• Translate complex financial data into clear narratives, enabling informed decision-making by senior stakeholders.

• Serve as a thought partner to leadership, bringing strategic insights and financial acumen to portfolio discussions.

• Manage tools and systems used for budget tracking, headcount reporting, and analytics (e.g., Excel, Power BI).

• Lead continuous improvement initiatives to streamline financial and headcount reporting processes.

Qualifications:

• A minimum of a Bachelor's degree is required, preferably in a scientific, business or technical discipline.  Master's degree preferred.

• A minimum of 8 years of related work experience in the pharmaceutical or healthcare industry or Contract Research Organization (CRO) is required.

• Budgeting and planning experience is required.

• Advanced Excel for financial modeling, forecasting, and scenario planning is required.

• Experience with Power BI or Tableau for building dashboards and visualizing budget/headcount data is required.

• Strong data analysis skills, including variance analysis and benefit realization metrics, is required.

• Experience with headcount tracking tools and integration with HR systems (e.g., Workday) is required.

• Must have excellent verbal and written communication skills.

• Must have strong analytical and problem-solving skills.

• The ability to analyze data and translate insights into dashboards is required.

• The ability to collaborate effectively with all levels and influence decision-making across a global, matrixed organization is required.

• This position will require up to 10% domestic and international travel.

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