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Bioprocess Engineer
2 weeks ago
Cellcraft® is a B2B cultivated meat company based in Cambridge tackling global food security and sustainability challenges. Our AI-driven bioelectronic technology powers the Cellcraft® Farm: an end-to-end, scalable Cultivated Meat (CM) Manufacturing Platform to empower food producers to make their own delectable, sustainable cultivated meats locally. Cellcraft is the world’s first cultivated meat company with a focus on software and analytics. We believe the future of meat must be both sustainable and irresistible.As a Bioprocess Engineer, you will play a key role in developing, optimising, and scaling bioreactor-based processes for cultivated meat production. You will be adaptable and able to handle a range of cross-functional projects in other functional areas including cell line and media development, assay development, and downstream processing, to ensure robust, efficient, and scalable production systems.Cellcraft is a fast-paced environment. You must be a problem solver capable of applying initiative who enjoys seeing their ideas come to fruition.TasksDesign and execute bioprocess experiments for the development and optimisation of single cell and aggregate cell cultivation in stirred tank and 3D bioreactors.Develop and implement process control strategies (pH, dissolved oxygen, feed strategies, agitation, etc.) to maintain robust cell growth and differentiation.Lead maintenance and suspension adaptation of cell lines to enable scalable bioprocessing.Support translation of laboratory-scale processes into scalable, manufacturable systems.Support process transfer, scale-up, and tech transfer to manufacturing partners.Analyse process data, generate technical reports, and present findings to internal stakeholders.Contribute to, and evaluate bioreactor system design, including hardware, sensors, and automation integration.Ensure processes comply with food safety and regulatory requirements.RequirementsRequired experience:Bachelor’s or Master’s degree in Biology, Bioprocess Engineering, Biotechnology, or a related field.A PhD or equivalent industrial experience in cell culture, bioprocessing, fermentation, or related biomanufacturing environments.3+ years’ hands‑on experience in setting up and operating stirred tank bioreactors in cell therapy, biologics, or food biotech.Proven hands‑on expertise in aseptic adherent and suspension cell culture techniques.Strong knowledge of mammalian cell biology, growth kinetics, bioreactor design, and process scale‑up.Hands‑on experience with bench‑scale bioreactors.Strong knowledge of measurement, optimisation, and scaling of bioreactor parameters including mass transfer (kLa), pH, temperature, agitation (tip speed, power input), shear force, metabolomics etc.Experience with process analytical technologies (PAT), automation, and process modelling.Strong analytical, problem‑solving, and data interpretation skills.Passion for sustainable food and advancing cultivated meat technologies.Desirable experience:Design and operation of continuous perfusion within bioreactor systems.Culture of induced pluripotent stem cells and other immortalised cell lines.Knowledge of myogenic and adipogenic differentiation.Tissue engineering including 3D organotypic culture.Experience with media and cell line development.Understanding of computational modelling of fluid dynamics, cell growth and other phenomena within bioreactors.Sourcing and procurement of materials and equipment for bioreactors.BenefitsCompetitive compensation and stock optionsPrivate health InsurancePotential for excellent career progressionExposure to an up‑and‑coming disruptive and innovative marketOpportunity to be at the forefront of the cultivated meat industry and make a tangible impact on global sustainability.Join Cellcraft as a Bioprocess Engineer and revolutionize cultured meat innovation in Cambridge. Be part of a dynamic team at the forefront of biotechnology research, backed by leading VCs.Cellcraft is an Equal Opportunities Employer. We are committed to creating inclusive teams and providing a work environment that allows all to be themselves.Our Values🥩 COMPASSIONATE DRIVEWe put people at the core of our push for change. Focusing on the needs of living beings and our planet, rather than indulging in the abstract. We embody this without compromise, every single day.👩🔬 INVENTIVE VISIONWe foster a highly innovative environment, accelerating creativity and novel ideas which deliver inventive and refreshing solutions for good. We are going against the grain: advocating visionary ideas which disrupt the status quo. We endorse revolutionary thinking and doing.🔬 SCIENTIFIC RIGOURScience is the pursuit of the uncompromising truth, and so this is where we have set the bar in all aspects. At our company, scientific rigour is not just a value - it is a superpower. Our attention to details and meticulous testing is the secret sauce that make our technologies so mouth‑wateringly good.🧬 POLYMATH SPIRITOur work demands myriad skills and expertise, enabling us to deliver impact to our partners holistically, across their complex value chains. We value the insights arising from different backgrounds, and our current team comprises members from many different nations with expertise across multiple disciplines - from bioelectronics to fluid dynamics. #J-18808-Ljbffr
