Principal Scientist Cell-based Assays

1 week ago


Potters Bar, United Kingdom NHS Full time

Principal Scientist Cell-based Assays Medicines and Healthcare Products Regulatory Agency (MHRA) is seeking a Principal Scientist to lead a team of analytical scientists focused on cell‑based assays for the characterisation of biological medicines. Key responsibilities Ensure analytical assays are performed in compliance with ISO17025, including assay development, validation and troubleshooting. Manage day‑to‑day implementation and delivery of improvements in patient outcomes through resource organisation, process improvement and changes in working practice, including training and innovative assay development. Advise, supervise and train staff in specific assays and the administration of control testing. Engage with stakeholders across the agency, national control laboratories and manufacturers to ensure quality of service and patient access to medicines. Qualifications and skills Extensive experience working within a ISO17025 quality management system. Extensive experience with fluorometric, microscopy, foci‑forming assays, fluorescence‑activated cell sorting (FACS), plaque‑forming and plaque‑reduction neutralisation assays. Experience using a Laboratory Information Management System (LIMS) and analysing large complex data sets. Strong leadership skills, ability to create a collaborative environment and respond effectively to change. Excellent communication skills and ability to engage a wide variety of stakeholders. PhD in a relevant field or equivalent extensive experience with analysis of biological medicines, including vaccines. Employment details Location: South Mimms, Hertfordshire, UKType: Full‑time permanentClosing date: 14 December 2025 How to apply Please apply through the MHRA website – NHS Jobs applications will not be accepted. Contact For assistance applying, contact careers@mhra.gov.uk #J-18808-Ljbffr



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