Principal Research Scientist I, Analytical R&D

3 days ago

Worcester England United Kingdom ZipRecruiter Full time

Job Description

Company Description:

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and TikTok.

Position Description:

For the Principal Research Scientist I position, we are seeking a highly motivated, experienced analytical scientist to be an Analytical Project Leader in New Chemical Entities (NCEs) drug substance and drug product in both preclinical and clinical programs. The candidate should have extensive expertise within an R&D environment with a fit for purpose mindset. Familiarity with solid oral dosage forms including nanoparticles, amorphous systems, and lipids is expected. Experience with lipid nanoparticles is a plus.

He/she should be able to conceive, execute and communicate novel multi-disciplinary research or development strategies that achieve project and strategic goals. Serve as an analytical project leader and contribute scientific insights on discovery programs with candidate compounds moving to clinical.

He/she must foster productive collaborations within the global Analytical R&D organization and with R&D cross-functional partners such as Discovery, Pre-Clinical Safety, Process Chemistry, Process Engineering, Molecular Profiling and Drug Delivery, Drug Product Development, and Quality Assurance and CMC-Regulatory.

Qualifications:

  • Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 14 (BS), 12 (MS), or 6 (Ph.D.) years related industry experience.
  • Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshooting analytical methods.
  • Experience with analytical approaches toward physicochemical characterization of pharmaceutical dosage forms (i.e. HPLC, UPLC, MS, DSC, TGA, DVS, PXRD, dissolution).
  • Knowledge of preclinical and clinical formulation development principles relevant to lipid nanoparticle (LNP) formulations - demonstrated industry experience strongly preferred.
  • Working knowledge of typical formulation approaches and routes of administration (i.e. IV, SC, IP, PO) across multiple species.
  • Familiarity with the role that physicochemical properties play in drug delivery and formulation design.
  • Demonstrate creative 'out of the box' thinking to solve difficult problems.
  • Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
  • High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Additional Information:

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

  • This is an on-site opportunity located at AbbVie Bioresearch Center (ABC) in Worcester, MA.
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remain in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, sex, national origin, age, disability, genetic information, or expression, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html.

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html.

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