Senior Bioinformatics Scientist

Senior Bioinformatics ScientistLocation: San Francisco, CAEmployment Type: Full-TimeDepartment: EngineeringOverviewWe are proud to be partnering with an industry-leading biotechnology innovator whose mission is to accelerate global research through powerful, next-generation DNA sequencing and analysis tools. Their technology supports thousands of scientists - from fast-growing startups to academic labs - helping advance critical discoveries and improve health outcomes worldwide.As a Senior Bioinformatics Scientist, you will bring deep technical expertise and a creative mindset to design, build, and optimize high-throughput bioinformatics workflows. Working in close collaboration with scientists, engineers, and product teams, you will help shape the future of bioinformatics infrastructure, enabling faster and smarter science.ResponsibilitiesDevelop, maintain, and optimize state-of-the-art sequence analysis workflows capable of processing thousands of samples per dayIntegrate and evaluate new bioinformatics tools to improve accuracy, speed, and scalability of pipelinesTroubleshoot and resolve complex challenges related to sequencing data, including biological artifacts and platform-specific edge casesTranslate raw bioinformatics outputs into actionable, clear, and user-friendly reports, visualizations, and interactive toolsMentor and support junior team members while continuously growing your own technical skill setCollaborate cross-functionally to develop and deliver new product featuresWrite clean, maintainable, production-ready codeContribute to a culture of innovation, curiosity, and scientific excellenceRequirementsEducation & Experience:PhD in a biological science or related discipline8+ years of experience developing production-scale bioinformatics pipelinesTechnical Skills:Deep experience in bulk and single-cell RNAseq analysis, including differential expression workflowsProven expertise in developing Snakemake or Nextflow pipelines deployed in local and/or cloud environmentsSolid understanding of molecular biology and sequencing technologies (Illumina, Oxford Nanopore)Proficiency in Python (including numpy, pandas, biopython, Jupyter) and Conda environmentsFamiliarity with Docker/Singularity, Git, and Linux shell scriptingStrong knowledge of core sequence analysis concepts (alignment, assembly, QC)Experience with large-scale genomic data processing and public genomic repositoriesAbility to develop intuitive web-based reporting or visualization tools (e.g., R Shiny, Streamlit)Clean, maintainable, production-grade coding practicesPreferred Qualifications:Experience developing performant software in a compiled language (C++, Rust, etc.)Interest in advanced data visualization and intuitive UX1+ year of experience in a molecular biology wet-lab environmentDemonstrated ability to develop novel bioinformatics algorithmsBenefitsCompetitive salaryEmployee stock options4 weeks paid time off + 10 paid holidaysComprehensive health, dental, and vision insurance(k) with company matchingLife insurance, mental health support, health advocacy servicesGym membership reimbursementWhy Apply?Contribute directly to accelerating world-changing biotech researchWork in a collaborative, inclusive, mission-driven teamLeverage cutting-edge tools and methodologies in a high-impact environmentWe encourage applications from diverse and creative thinkers who thrive in collaborative, inclusive teams. If you'd like to learn more, please apply today or reach out in confidence to discuss further.