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Research Scientist
1 month ago
We are seeking a highly motivated Postdoctoral Researcher to join the Wood and Sanders Groups in the Department of Paediatrics at the University of Oxford. The successful candidate will work under the supervision of Professor Matthew Wood and Professor Stephan Sanders to develop molecular therapies for disorders of the nervous system and muscle. Our objectives include understanding disease biology, identifying and validating therapeutic targets, and developing gene-based nucleic acid therapeutic platforms. The laboratory uses in-vitro and in-vivo models to evaluate these platforms and simultaneously develops advanced delivery technologies to target relevant tissues and cells, such as skeletal muscle, heart, and nervous system. The laboratory has developed novel oligonucleotide and RNA editing therapies for neuromuscular disorders, including Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy type 1 (DM1), Spinal Muscular Atrophy (SMA) and Spinal and Bulbar Muscular Atrophy (SBMA). The group has also developed extracellular vesicle nanotechnologies for targeted cell delivery and discovered delivery technologies, including peptide and antibody-based technologies. Research in the laboratory also includes studying fundamental RNA biology and developing RNA-based therapeutic agents and novel technologies for their delivery. The post will be managed by Prof Carlo Rinaldi. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. This position is offered full-time on a fixed-term contract initially until further notice with the possibility to extend provided further external funding is available.
About the department
The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. The department is part of the Medical Sciences Division at the University of Oxford and is committed to advancing our understanding of child health and developing new treatments for childhood diseases.
