Modelling & Simulation Engineer - Medical Devices

1 day ago


Leeds, Leeds, United Kingdom adsilico Limited Full time
About the Company

At adsilico Limited, we're pushing the boundaries of medical device innovation by harnessing the power of in silico technologies. Our mission is to redefine the medical devices industry by accelerating the creation of new devices, enabling radical innovation, and reducing costs. We're passionate about technology that impacts lives.

Our team is diverse and inclusive, and we value excellence and ethics in equal measure. We're backed by a motivated and experienced investor consortium, a world-class advisory board, and competitive funding from Innovate UK.

About the Job

As a modelling & simulation engineer at adsilico Limited, you'll be at the forefront of our efforts to create scalable simulation technologies that leverage our cutting-edge virtual patients. You'll design and implement techniques for simulating medical device interventions on populations of virtual patients, from developing and validating underlying model components to deploying these in automated and efficient workflows. You'll focus on devices for cardiovascular diseases and have a passion for impacting healthcare through commercial translation of state-of-the-art developments in modelling & simulation.

Responsibilities
  • Develop efficient and reliable models of the behaviour of cardiovascular medical devices and of relevant patient tissues and fluids.
  • Design and execute rigorous verification and validation strategies for these models according to relevant standards and regulatory guidance.
  • Develop automated computational workflows for creating and executing large-scale simulation studies for predicting device performance on populations of virtual patients.
  • Design and implement tools for analysing and reporting on simulation results.
  • Contribute to development of formalised standards of practice for modelling & simulation within the company which reflect relevant industry standards and regulatory requirements.
  • Keep abreast of the latest advances in modelling & simulation, and ensure our methodologies reflect the state-of-the-art.
  • Collaborate with the regulatory affairs team to ensure simulations meet regulatory requirements.
  • Implement good documentation practices based on quality management processes.
  • Consult and collaborate with cross-functional technical, data, and R&D teams to ensure harmonised development of algorithms and technology infrastructure across the organisation.
  • Contribute to scientific publications and conference presentations that establish adsilico Limited's thought leadership.
  • Communicate technical concepts to both expert and non-expert internal and external stakeholders.
Requirements
  • Ph.D. in a relevant field (engineering, computing, mathematics, physics, etc.).
  • Or: Master-level degree or equivalent in a relevant field and 4 years' industry experience of directly related modelling & simulation.
Desirable
  • Proven experience of computational modelling & simulation with a focus on medical devices, preferably in an industry setting.
  • Solid understanding of theoretical principles underpinning nonlinear finite element analysis (FEA) and proficiency in the use of at least one major FEA software package (Ansys/LS-Dyna preferred).
  • Proficiency in Python programming and in creation of efficient and well-documented scripts for model creation and execution.
  • Familiarity with the ASME V&V40 standard for assessing model credibility in medical device simulation, and with related FDA guidance.
  • Experience of following best practices for software development (e.g. use of Git for code version control).
  • Experience of communicating research to expert and non-expert audiences.
Why Join Us?
  • Impact: Contribute to groundbreaking advances in in silico trials that will reshape the medical devices industry and bring innovations to patients faster and more safely than ever before.
  • Entrepreneurial Environment: Be part of a cutting-edge start-up that values creativity, collaboration, and agility; make your mark.
  • Research-Driven Innovation: Work with a world-class scientific team to shape products and services based on cutting-edge research.
  • Upskilling: Get exposure to and training in highly valued areas, such as quality management and regulatory affairs to accelerate your career in a fast-growing field.
  • Location: Take advantage of our modern and well-positioned office in Leeds, UK, balanced with hybrid working opportunities.
  • Compensation: Receive a highly competitive package.


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