Senior Scientist

3 weeks ago


Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full time

We are seeking a highly skilled and experienced Senior Scientist to join our Regeneron Cell Medicine team. As a key member of our research group, you will play a critical role in advancing our cell therapy programs and developing innovative solutions to improve our platforms and future programs.

Key Responsibilities:

  • Leverage molecular biology techniques to design and generate lentiviral vectors using proprietary platform technology.
  • Design and execute experimental plans to characterize TCR- and CAR-based T cell products through cell-based assays and other relevant procedures.
  • Maintain detailed and timely records of experimental protocols, results, and observations.
  • Collaborate with the team to troubleshoot technical issues and propose creative solutions to overcome obstacles.
  • Stay informed about the latest scientific advancements and apply relevant technologies to improve experimental processes.

Requirements:

  • Ph.D. in Immunology, Cancer Biology, Molecular Biology, or a related field.
  • 0-3 years of relevant experience or a BS/MS and 8-10+ years of relevant experience.
  • Hands-on experience with LV-vector construct design, cloning, vector production, and mastery of basic molecular biology techniques.
  • Experience with cell-based assays and functional assays measuring T cell activation, cytokine release, proliferation, survival, and tumor cell killing.
  • Knowledge of standard TCR/CAR-T cells culture technique and experience developing and applying complex flow cytometry panels for the characterization of TCR/CAR-T cells.

What We Offer:

  • A dynamic and collaborative research environment.
  • Opportunities for professional growth and development.
  • A competitive salary and benefits package.

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