Computational Chemist Position

3 weeks ago


London, Greater London, United Kingdom Barrington James Full time
Job Overview
Barrington James is currently working with an innovative biotech company specializing in leveraging generative AI and quantum physics algorithms for rapid and innovative drug discovery. We are looking for a highly skilled Senior Computational Chemist to join their team in London.

About the Role
As a Senior Computational Chemist, you will be responsible for utilizing computational methods to design and generate small molecules targeting specific therapeutic goals. You will communicate hypotheses and work plans concisely, ensuring discussion and refinement, while prioritizing code robustness and reproducibility. Your tasks will include implementing and evaluating generative AI algorithms, property prediction models, and molecular dynamics techniques, providing structured feedback to enhance platform performance. Additionally, you will propose innovative strategies to enhance project progression for precision, speed, and scalability, coordinating with Contract Research Organizations (CROs) to optimize property predictions and synthesis feasibility. You will also collaborate closely with other members of the team, including Machine Learning engineers, software developers, computational chemists, and theoretical physicists. Furthermore, you will mentor junior team members to foster their development as drug discovery researchers.

About You
We are looking for a candidate with a Ph.D. in Computational Chemistry, Medicinal Chemistry, Machine Learning, or a related field, along with a minimum of 3+ years of industry experience working in a Drug Discovery environment. You should have hands-on experience using state-of-the-art methods, extensive knowledge of protein structures, functions, and protein-ligand interactions. Proficiency in computational chemistry packages, including RDKIT, GROMACS, MDAnalysis, etc., and small molecule ligand discovery and cheminformatics techniques is required. Intermediate to advanced proficiency in Python is essential.

Benefits
This is an excellent opportunity to work with a cutting-edge technology and contribute to the development of new medicines. You will have the chance to work on challenging projects, learn from experienced colleagues, and grow your skills and expertise. The estimated salary for this position is £80,000 - £110,000 per year, depending on experience.

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