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Senior Scientist

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Didcot, Oxfordshire, United Kingdom Etcembly Ltd Full time
Job Description

We are seeking a highly skilled Senior Scientist to join our team at Etcembly Ltd. As a Senior Scientist, you will be responsible for leveraging your expertise in molecular biology and display technology platforms to test and characterise novel TCR molecules as potential drug candidates.

You will draw upon your experience in display-based screening to provide insightful strategies towards effective data mining and triaging. The ideal candidate will have a strong drive and motivation to deliver, and as a seasoned and experienced scientist, you will be supporting various cross-functional projects.

Key Responsibilities:

  • Employ in vitro display techniques for high throughput library screening, using guidance from experimental and computational data
  • Develop tailored biochemical screening assays for specific applications
  • Establish a robust workflow for TCR profiling, including potency and specificity screening methods
  • Participate in scientific strategy planning and contribute to new ideas
  • Document experimental data and effectively communicate scientific results through reports and presentations
  • Troubleshoot experiments with minimal supervision and propose strategies to progress ongoing projects
  • Follow and write protocols and SOPs
  • Keep up to date with the scientific literature and developments in the field

Experience and Skills:

  • PhD in a relevant discipline with postdoctoral experience and/or relevant industrial research experience (e.g. in biologics development), or an MSc with comparable experience
  • Strong molecular biology experience, including proficiency in library generation and QC, Next-Generation Sequencing techniques, and variant screening/selection methods
  • Proven expertise in at least one protein display methods (e.g. phage, yeast, mammalian)
  • Demonstrable experience in leading and advancing projects
  • Adaptable mindset to be flexible in the face of evolving priorities
  • A highly motivated and proactive individual who is invested in the success of the team
  • Excellent verbal and written communication skills
  • Ability to work independently and in a collaborative team

What We Offer:

  • Opportunity to work at the cutting edge of AI and protein engineering, shaping the future of drug discovery and biotechnology
  • Competitive salary and equity package
  • State-of-the-art computational resources and access to cutting-edge biological datasets
  • Collaborative and innovative work environment
  • Opportunities for continued learning and professional development
  • Based at Harwell Campus with a comprehensive benefits package