Senior Research Scientist
1 month ago
Immunotherapy Development Specialist
Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.
We are exclusively partnered with an innovative biotech start-up, recently spun out of the University of Oxford, on a mission to redefine the sensitivity of Chimeric Antigen Receptors (CARs) and T-Cell Receptors (TCRs) to better target high-value antigens. Our goal is to push the boundaries of TCR and CAR engineering, creating next-generation immunotherapies with unmatched specificity and efficacy in solid tumors and other high-value indications.
Key Responsibilities
- Lead and execute in vitro potency assays and functional assays to evaluate and enhance the sensitivity of engineered CARs and TCRs against specific targets.
- Design and conduct complex preclinical studies, optimizing protocols for TCR-T and CAR-T cell development.
- Perform high-throughput screening, cellular proliferation, and cytotoxicity assays to validate efficacy and specificity of TCR-T/CAR-T candidates.
- Develop and refine methodologies for immunophenotyping, flow cytometry, and cytokine release assays, evaluating cell therapy constructs under diverse conditions.
- Analyze and interpret complex data, generating insights to guide further engineering efforts and ensure product quality.
- Collaborate closely with cross-functional teams in cell engineering, bioinformatics, and translational research.
- Stay abreast of recent advances in T-cell engineering and immuno-oncology, contributing innovative ideas to the strategic R&D roadmap.
Requirements
- Ph.D. in Immunology, Cell Biology, Molecular Biology, or a related field, with 3+ years of relevant biotech or pharma experience; MSc with significant biotech experience may also be considered.
- Hands-on experience with CAR-T or TCR-T cell development, ideally in preclinical settings within biotech or start-up environments.
- Expertise in in vitro potency assays, functional assays, cytotoxicity, and cytokine release assays.
- Proficiency in flow cytometry, immunophenotyping, and other cell-based assays to characterize engineered T cells.
- Demonstrated ability to work independently, interpret complex data, and generate actionable insights.
- Collaborative mindset, excellent communication skills, and ability to thrive in a dynamic start-up environment.
Northreach is an equal opportunity employer and we do not discriminate against any employee or applicant for employment based on race, colour, religion, sex, national origin, disability, or age. We are committed to promoting diversity, equity, and inclusion in the workplace and hiring practices, therefore only partner with businesses that promote DEI. We strive to create a welcoming and inclusive environment for all employees.
-
Senior Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timeImmunocore's Senior Research Scientist RoleWe are seeking a highly skilled Senior Research Scientist to join our team at Immunocore. As a talented molecular biologist and innovator, you will be responsible for providing deep scientific and technical expertise in antibody research, including antibody fragments such as scFv and VHH, bispecifics, and...
-
Senior Research Scientist
6 days ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeResearch Scientist Opportunity at the University of OxfordWe are seeking a highly skilled and motivated Research Scientist to join our multidisciplinary team at the University of Oxford. This is an exciting opportunity to work with Professor Lars Fugger and his team at the Weatherall Institute of Molecular Medicine.In this role, you will have access to...
-
Senior NGS Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Taylorollinson Full timeJob Title: Senior NGS Research ScientistJob Summary:We are seeking an experienced NGS Research Scientist to join our team at Taylorollinson. As a key member of our R&D team, you will be responsible for leading technical projects and overseeing the development of NGS assays.Key Responsibilities:Act as technical lead on R&D projects for the improvement and...
-
Oxford, Oxfordshire, United Kingdom IC Resources Full timeIC Resources seeks a highly skilled Senior AI Research Scientist in Oxford, UK to accelerate scientific simulations using minimal data and high accuracy.Company OverviewWe are a leading provider of innovative solutions for industrial products. Our mission is to push the boundaries of technology and make a real impact.Job SummaryThis is an exciting...
-
Senior Machine Learning Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom IC Resources Full timeJob Title: Senior Machine Learning Research ScientistJob Description:IC Resources is seeking a Machine Learning Research Scientist to join our client in the UK, developing neural network technology to accelerate expensive scientific simulations with minimal data and high accuracy.Key Responsibilities:Develop machine learning frameworksReplicate and integrate...
-
Senior Research Scientist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Moderna Therapeutics Inc. Full timeAt Moderna Therapeutics Inc., we are seeking an exceptional Senior Research Scientist to join our team in the development of cutting-edge mRNA medicines. As a member of our dedicated research team, you will be responsible for advancing the technological frontier of mRNA medicines and contributing to the creation of a leading-edge research, development, and...
-
Postdoctoral Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeWe are seeking an exceptional Postdoctoral Research Scientist to contribute to our pioneering research in cardiovascular medicine. The successful candidate will join our team of world-renowned experts in developing innovative treatments for inherited cardiomyopathy. Based within the esteemed University of Oxford Centre for Human Genetics, this fixed-term...
-
Postdoctoral Research Scientist
13 hours ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeBiological Science Research OpportunityA highly competitive salary of £50,000 - £65,000 per annum is available for this Postdoctoral Research Scientist position in Oxford, United Kingdom.We are looking for a talented researcher to join our team at the University of Oxford's Department of Biology. As a Postdoctoral Research Scientist, you will be...
-
Research Scientist
6 days ago
Oxford, Oxfordshire, United Kingdom Oxford Gene Technology Full timeJob OverviewAn exciting opportunity has arisen for a skilled Research Scientist to join our Oxford-based Research & Development team. Reporting to the Head of Development, you will play a crucial role in all aspects of new product development, including laboratory preparation, sequencing, bioinformatics, and data interpretation.This is an ideal position for...
-
Senior NGS Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Taylorollinson Full timeSenior NGS Research ScientistOur client is a leading provider of Next Generation Sequencing (NGS) solutions to support the ongoing development of genetic-based medicine. An opportunity has now become available for an experienced NGS scientist to join the company and support with the product development projects within their NGS platforms.The Role:The...
-
Senior Research Scientist
1 week ago
Oxford, Oxfordshire, United Kingdom CK Group Full timeJob OverviewCK Group is a leading biotechnology company based in Oxford, seeking an experienced Senior Scientist with a strong background in cancer biology to join their research team on a permanent basis.The Role:This position involves contributing to strategic R&D goals by designing, managing, and performing studies to support candidate development and...
-
Senior Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Moderna Therapeutics Inc. Full timeModerna is seeking a highly skilled Senior Research Scientist to support the development and validation of bioanalytical methods using LC-MS techniques for clinical studies. The ideal candidate will have a strong foundation in the regulated bioanalytical LC-MS/MS field and the ability to thrive in a fast-paced, scientifically stimulating environment.Key...
-
Senior Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timeAbout the RoleWe are seeking a highly skilled and motivated Senior Research Scientist to join our Translational Medicine team. As a key member of our team, you will be responsible for conducting experimental investigations using IHC or IF to analyze clinical trial and non-clinical tissue samples.Key Responsibilities:Conducting experimental investigations...
-
Biomedical Research Scientist
6 days ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeWe are seeking a highly skilled Biomedical Research Scientist to join our vibrant research environment at the University of Oxford. Our team is focused on advancing pandemic sciences through cutting-edge research and innovation.As a Biomedical Research Scientist, you will be responsible for conducting independent research in one of four major research areas....
-
Senior Researcher
1 month ago
Oxford, Oxfordshire, United Kingdom CV-Library Full timeWe are seeking a highly skilled Senior Scientist to join our team at CV-Library in Oxford, UK. As a Senior Scientist, you will play a key role in the development of innovative immunotherapies for the treatment of solid tumors and other high-value indications.Key ResponsibilitiesDesign and execute in vitro potency assays and functional assays to evaluate and...
-
Research Scientist
3 weeks ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeWe are seeking a highly skilled Research Scientist to join our team at the Mathematical Institute, University of Oxford.The successful candidate will be part of a research group focused on derived algebraic geometry and/or homotopy theory, as part of the Royal Society grant "Tackling p-adic problems with partition Lie algebras".Responsibilities will include...
-
Senior Research Professional
6 days ago
Oxford, Oxfordshire, United Kingdom Hyper Recruitment Solutions Full timeWe are seeking a highly skilled Senior Scientist to join our team at Hyper Recruitment Solutions.About the RoleThe Senior Scientist will be responsible for developing, optimizing, qualifying, and validating analytical methods to evaluate drug substances and drug products from preclinical through late-phase clinical development.Key Duties and...
-
Senior Research Scientist
1 month ago
Oxford, UK, Oxfordshire, United Kingdom NDC Tek Full timeGo Tek are currently on the lookout for a talented Senior Research Scientist with experience in Protein Design and Enzyme Engineering for an AI Biotech Start-Up company. They're at the forefront of the AI-generated enzyme design revolution and you'll play a crucial part in taking this business to the next level. Responsibilities:Assist with...
-
Postdoctoral Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom ProImmune Full timePostdoctoral Research ScientistWe are seeking a highly skilled Postdoctoral Research Scientist to join our R&D team at ProImmune. As a key member of our team, you will play a crucial role in the development of new products and services.Key Responsibilities:Conduct research in protein biochemistry, molecular biology, and cell biologyDevelop and implement new...
-
Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Evox Therapeutic Full timeJob Title: Scientist/Senior ScientistCompany: Evox TherapeuticJob Summary:The Research Scientist will play a key role in advancing Genome Editing technology, delivered by exosomes, towards pre-clinical and clinical studies. The successful candidate will apply various loading strategies to deliver Genome Editing therapeutics, contributing to the development...