Genomics Bioinformatician

2 weeks ago

London, Greater London, United Kingdom Homerun B.V. Full time
About the Job

We are seeking a highly skilled Genomics Bioinformatician to join our team at Homerun B.V. in London. As a key member of our data science and genomics team, you will play a crucial role in helping us achieve our goal of building the largest and most comprehensive biodiversity knowledge store.

The successful candidate will take ownership of our sequencing and metagenomic data analysis production operations, working closely with all teams at all data collection and analysis points. This will include collaborating with our biodiversity partners, field scientists, sequencing ops, ML scientists, and commercial stakeholders.

Responsibilities
  1. Develop and run software to support the biodiversity and sample collection teams and genome sequencing operations.
  2. Take ownership in building, improving, and managing the in-house genomic assembly and annotation pipeline.
  3. Manage and audit the data workflow of our samples from collection to data warehousing, including quality control of appropriate files and datasets.
  4. Collaborate with the Data Engineering team in building and managing the pipeline in our in-house designed infrastructure platform.
  5. Investigate, benchmark, and integrate novel analyses into the pipeline.
  6. Write and document high-quality code and methodology of processes.
  7. Develop methods to leverage in-house sequencing datasets to create full high-quality genomes for context analysis.
Requirements
  • A graduate degree in the life sciences, computer science, or a similar field.
  • At least three years of experience in a high-throughput sequencing environment and building and managing genomics and protein analysis workflows or pipelines.
  • Knowledge of DNA sequencing platforms (second and third generation) and experience working with their data types.
  • Experience and knowledge of Unix-based operating systems, libraries, and tools.
  • Knowledge and/or experience of tools used in bioinformatics, both in genomics, metagenomics, and/or protein biology.
  • Experience with a programmatic scripting language (Python, Perl, etc.) and shell scripting.
  • Fluency in English.
Advantages
  • Experience with metagenomic data and knowledge of microbial genomics and/or protein biology.
  • Experience with data workflow management systems such as Prefect, Airflow, Snakemake, Nextflow, but preferably Dagster.
  • Experience in the techbio/biotech industry that is focused on product development (therapeutics, protein/drug discovery, CRO, etc.).
  • Experience with building databases (relational and/or non-relational).
  • Experience using cloud solutions (AWS, GCP, etc.).
  • Experience with Agile software development.

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