Vector Process

4 weeks ago


Abingdon, Oxfordshire, United Kingdom Adaptimmune Full time

About Adaptimmune

Adaptimmune is a biotechnology company focused on developing novel immunotherapies for cancer. Our innovative approach utilizes engineered T cells to target and destroy tumor cells, offering a potentially curative treatment option for patients.

The Role: Vector Process & Analytical Development Scientist

We are seeking a highly motivated and experienced Scientist to join our growing Vector Process & Analytical Development (PD&AD) team. This role will contribute to the development and optimization of our lentiviral vector manufacturing process, as well as the establishment and validation of analytical assays for characterization and release testing.

Key Responsibilities:

  • Plan and execute experiments to advance the development of our lentiviral vectors.
  • Collaborate with senior scientists to analyze experimental data, draw conclusions, and summarize findings.
  • Maintain accurate records of experimental procedures, results, and observations.
  • Perform routine cell culture maintenance, including mammalian cell lines used in vector production.
  • Contribute to the production and purification of lentiviral vectors using established protocols.
  • Ensure proper maintenance and calibration of laboratory equipment.

Qualifications & Experience:

  • Bachelor's degree in Life Sciences or a related field.
  • Minimum 3 years of relevant laboratory experience, preferably in a biotechnology or pharmaceutical setting.
  • Demonstrated experience with either viral vector characterization assays or vector production/purification methods.
  • Proficiency in various laboratory techniques, including mammalian cell culture, ELISA, nucleic acid extraction, qPCR, flow cytometry, and bioprocessing.

Desirable Skills:

  • Experience working within a regulated environment (e.g., GMP).
  • Familiarity with regulatory guidelines and expectations for assay or process validation.

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