Senior Translational Data Scientist

5 days ago

Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full time
Job Summary

We are seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team at Bicycle Therapeutics. This individual will lead the development, customization, and maintenance of a biomarker software solution to support our clinical-stage oncology portfolio assets.

Key Responsibilities
  • Lead the Development of Biomarker Software Solutions
    • Technically contribute to and strategically manage external programmers to develop data ingestion, processing, and wrangling pipelines
    • Lead the migration of internal R-scripts and Shiny apps onto the software solution
    • Support the integration, analysis, and visualization of biomarker and clinical data within and across targeted toxins and immune-oncology clinical trial programs
    • Provide platform training and support to Bicycle scientists
  • Support Data Management and Integration
    • Support data management and integration of translationally focused preclinical and clinical datasets (e.g. Nanostring, NGS)
    • Support reverse translation analytics activities by integrating relevant internal and external datasets as well as developing clear analyses and visualizations
  • Collaborate with Cross-Functional Teams
    • Work in a cross-functional environment and communicate effectively across project teams that consist of data scientists, translational scientists, IT managers/analysts, pharmacologists, clinical
  • Document Data Transfer Specs and Analysis Processes
    • Effectively document data transfer specs, R scripts, and data analysis processes
Qualifications
  • Essential Qualifications
    • Experience building, customizing, and/or using clinical biomarker software solutions
    • Strong computational skillset, including proficiency in at least one coding language (ideally R), and ability to perform the following tasks:
      • data ingestion, wrangling, integration, and analysis
      • design (both strategically and technically) bioinformatics pipelines
      • development of clear and effective data visualizations
      • understanding of Shiny apps (or other UI strategies)
    • Strong software engineering skills including familiarity with AWS, Posit, and Gitlab
    • Strong bioinformatics skills including experience analyzing sequencing data
    • Familiarity with the oncology field and oncology-focused biomarker datasets
    • Takes initiative, ask questions, and independently moves projects along in a fast-paced environment
    • Team player, conscientious, organized, and creative
  • Desirable Qualifications
    • Experience working with EDC and/or biomarker data from clinical trials
    • Experience in LSAF
Additional Information
  • We offer a competitive reward package, including annual company bonus, employee recognition schemes, and a range of benefits, including 28 days annual leave, employer contribution to pension, life assurance cover, private medical insurance, and enhanced parental leave policies.
  • We are committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company.

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