Senior Translational Lead

3 weeks ago


Stevenage, Hertfordshire, United Kingdom GlaxoSmithKline Full time
About the Role

We are seeking a highly motivated scientist with experience in haematology to join the Oncology Translational Research team in GSK Oncology. The successful candidate will work as part of a broad team that applies translational model systems through both internal and external partnerships to enable cancer patient risk stratification, identify biomarkers and predict future targeted and/or immuno-therapy susceptibilities.

Key Responsibilities
  • Translational Research Leadership: Represent Oncology Translational Research by acting as a haematology translational leader in cross-functional (global) matrix teams, leveraging deep expertise of the haematology field and clinical landscape.
  • Plan and Deliver Translational Research: Independently create translational research plans, implemented/delivered through both matrix and line leadership, to enable deep profiling of patient samples in order to address key asset team questions around mechanism, resistance and combination opportunities.
  • Engage with External Partners: Engage with external HCPs/Investigators in UK, Europe and USA through translational alliances to design and lead efforts for deep profiling of existing clinical cohorts/biobank material that will generate insights to guide future clinical studies.
  • Advise Pre-clinical Project Teams: Act as a translational advisor to pre-clinical project teams to enable early biomarker discovery/evaluation, support indication selection and identify pathways for differentiation vs competitive landscape.
  • Lead Technology Evaluation: Lead the external and internal technology evaluation of novel ex vivo haematology models to address key mechanistic questions aligned with the asset(s) you are supporting, taking responsibility for study design, validation and experimental implementation of the selected approaches.
  • Strong Leadership and Communication Skills: This role requires strong leadership skills along with deep translational research expertise as it is expected that the person will have decision making accountability for defining what translational work is conducted on the projects/alliances to which they are assigned, as well as the ability to communicate these translational plans in a clear, confident and succinct manner to cross functional matrix teams.


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