Advanced Therapies Bioinformatics Specialist

6 days ago


Oxford, Oxfordshire, United Kingdom Northreach Full time

Company Overview

Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.

Job Description

The Senior Bioinformatician will play a pivotal role in the conceptualization, design, and implementation of innovative data analysis strategies to advance our ERAP1 inhibitor-driven antigen discovery pipeline. This role involves analyzing extensive proprietary datasets, including immunopeptidomic, transcriptomic, and genomic data, to identify ERAP1 inhibitor-dependent targets for the development of MHC class I therapeutics.

  • Analyzing large-scale mass spectrometry data using nextflow pipelines.
  • Defining objectives and performing statistical analysis of data-dependent (DDA) and data-independent (DIA) immunopeptidomics assays.
  • Conducting analysis of parallel reaction monitoring (PRM) peptide assays.
Required Skills and Qualifications

We are seeking an exceptional candidate with a PhD (or equivalent experience) in bioinformatics, immunology, computational biology, or a related field. The ideal candidate should have:

  • In-depth knowledge of mass spectrometry-based proteomics data acquisition and processing.
  • Strong knowledge of machine learning and/or multivariate statistical modeling.
  • Proficiency in statistical programming and building statistical models.
  • Expertise in R or Python programming.
Benefits

Northreach offers a competitive salary range of $120,000 - $160,000 per year, depending on experience, as well as opportunities for professional growth and development. We are committed to promoting diversity, equity, and inclusion in the workplace and hiring practices.



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