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    3 weeks ago


    Manchester, United Kingdom Yourgene Health Full time

    About Yourgene HealthYourgene Health is a leading integrated technologies and services business, enabling the delivery of genomic medicine. We work in partnership with global leaders in DNA technology to advance diagnostic science.Job Title: Scientist IIWe are seeking a highly skilled Scientist II to join our PCR Diagnostics Team at Manchester Science Park....


  • Manchester, United Kingdom Yourgene Health Full time

    Job Title: Scientist II Position in PCR Diagnostics TeamAbout the Role: Yourgene Health, part of the Novacyt Group, is seeking a skilled Scientist II to join our PCR Diagnostics Team at Manchester Science Park.Key Responsibilities: Design and develop in vitro PCR diagnostic products/services for use in a range of applications to high quality and in a timely...

Scientist II

2 months ago


Manchester, United Kingdom Yourgene Health Full time

About Yourgene Health

Yourgene Health is a leading integrated technologies and services business, enabling the delivery of genomic medicine. The group works in partnership with global leaders in DNA technology to advance diagnostic science.

Our Mission

We primarily develop, manufacture, and commercialise simple and accurate molecular diagnostic solutions, for reproductive health, precision medicine and infectious diseases. Our flagship in vitro diagnostic products include non-invasive prenatal tests (NIPT) for Down's Syndrome and other genetic disorders, Cystic Fibrosis screening tests, invasive rapid aneuploidy tests and DPYD genotyping.

Our Expertise

We have a range of innovative DNA sample preparation platforms, powered by Ranger Technology, the Yourgene LightBench and Yourgene QS250, ideal for cell free DNA applications in NIPT and oncology including liquid biopsy.

Our Services

We also have a global laboratory service network equipped to be a full life-cycle partner for clinical, research and pharmaceutical organisations to support partners at the preclinical, clinical, and post market stage to develop, manufacture, obtain regulatory approval and commercialise new products and services. In addition, we offer NIPT and high throughput Covid testing service.

Our Culture

We are a growing, vibrant and exciting place to work, we are looking for committed driven individuals to be part of our next growth journey. Our culture is described by our employee's as collegiate, friendly, professional, innovative, open and fast paced. We have various social and well-being initiatives run by our Social Huddle that keep our sense of community alive during challenging times.

Job Summary

We are recruiting for a Scientist II within our OEM team based at Manchester Science Park. The Scientist II will perform office based and laboratory-based activities in the design, development, verification and validation of in vitro diagnostic products and services. The Scientist will assess supplied data and produce required reports and documents for the design and development of in vitro diagnostic products and services.

Key Responsibilities

  • Provide scientific expertise and input into the assessment and development of products and services.
  • To contribute to all development phases of a project while considering the bigger picture.
  • Lead planning, execution and reporting of work packages for new products and services.
  • Accurate and timely documentation.
  • Summarization of large amounts of external data into report formats.
  • Design of validation and assessment methods and validation of new products and services.
  • Setting of Quality Control Specifications and design of methods.
  • Work collaboratively with R&D scientists to create products and processes which meet the user needs of our customers.
  • Cross functional collaboration with Product Management, Product Operations and other functions where required.
  • Produce documentation for internal and external use.
  • Create, maintain and improve of laboratory SOPs, as well as systems and process SOPs.
  • Design and execute effective and efficient studies involving;
  • Accurate and timely documentation.
  • Developing and implementing protocols to show that tests meet acceptance criteria.
  • Processing clinical samples to demonstrate clinical validity.
  • Data generation, ensuring integrity and organized data management.
  • Provide accurate and independent data interpretation, building experience of systems-level thinking.
  • Determining test parameters, such as output specifications.
  • Meeting regulatory or other requirements.
  • Lead troubleshooting activities when technical issues arise.
  • Participate in activities outside of own team depending on business needs.
  • Perform laboratory maintenance tasks such as lab maintenance, stock monitoring, goods in receiving and cleaning.
  • Ensure own work meets regulatory & quality requirements (including compliance to SOPs, documentation using lab books, study plans, study reports and integrity of data).
  • Support and provide guidance to junior staff.

Requirements

  • Degree or further degree (or equivalent) in a life science such as molecular biology, biochemistry or genetics.
  • Typically 5+ years of relevant experience.
  • Experience in the development, verification and validation of molecular diagnostic assays in adherence with CE marking and/or design control regulations.
  • Experience working within a regulated environment.
  • Hands on experience with at least two molecular biology-based assays and techniques.
  • Capable of analysing data and providing interpretation.
  • Capable of independently performing experimental design and execution.
  • Enthusiasm, drive, thoroughness, diligence and a willingness to take personal responsibility to ensure that projects are successful.
  • Good organisational skills and thrives on working to tight timelines.
  • Can summarise scientific data in written form to effectively communicate plans, progress and ideas with Management, Peers or External Audiences.
  • Good IT skills, including Microsoft Office suite.