Manufacturing Process Specialist
3 weeks ago
In this Sr. Scientist role, you will be instrumental in the set-up and handling of bioreactors and the development of scalable upstream manufacturing processes.
About the Company:Spur Therapeutics is a global biotech company with research facilities and offices in the UK and the US. We are dedicated to developing transformative gene therapies for patients worldwide.
Key Responsibilities:This role involves working independently and as part of a team in a lab-based setting. Key responsibilities include setting up and handling bioreactors, manufacturing research/nonclinical grade viral vectors and recombinant proteins using mammalian cell suspension systems.
- Design and implement scalable upstream manufacturing processes using Design of Experiments (DoE)
- Collaborate with internal CMC teams for transfer of manufacturing and quality aspects from Research to CMC
- Develop and evaluate technologies and processes for AAV batches with improved yield, quality, and beneficial impurity profile
The ideal candidate will have a Ph.D. in a relevant discipline with >2 years of post-doctoral experience or at least 5 years of industry experience. They should have expertise in running bioreactors with suspension cultures of mammalian cells, particularly AAV manufacture.
Benefits:Estimated salary of £70,000 - £90,000 per annum, depending on experience, plus benefits including health insurance, retirement plan, and opportunities for professional growth.
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Manufacturing Process Specialist
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Manufacturing Validation Specialist
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