Computational Biologist

We are seeking an experienced Computational Biologist to join our team at GlaxoSmithKline. The successful candidate will lead the analysis of complex spatial biology datasets and accelerate the adoption of methods such as 3D histology and virtual staining.

About the Role

• Lead the analysis of 3D images to support investments in ex-vivo 3D imaging technologies and generate computational models for stain-to-stain transformation and virtual stain from un/stained digitally scanned images.
• Lead the analysis of data for defined spatial multiplex imaging project packages (multiplex IF, 10X Xenium/Visium).
• Generate analysis-ready data by processing raw data from GSK instrumentation – coding in R/python and develop ad-hoc bioinformatic code and validate publicly available software packages/scripts to help GSK extract maximum value from specific datasets.

Requirements

• Bachelor's degree in Life Sciences, Computer Sciences or related discipline.
• Experience in organs and organoids 3D image analysis in fixed samples and/or experience of Virtual staining and methods to digitally generate histological stains (H&E, Special Staining, IHC, IF).
• Experience in spatial multiplex imaging data analysis (multiplex IF, 10X Xenium/Visium).
• Experience with computer coding (R/python) and with complex mathematical concepts.

Salary and Benefits

The estimated salary for this role is £60,000 - £80,000 per annum, depending on experience. We also offer a range of benefits, including competitive bonus scheme, annual leave entitlement, pension plan membership and shares and savings programme.