Advanced Gene Editing Researcher

2 weeks ago

North East, United Kingdom ReCode Therapeutics, Inc. Full time
About the Role

We are seeking a highly skilled and motivated Postdoctoral Project Research Scientist to join our team at ReCode Therapeutics, Inc. in Durham, NC. The successful candidate will be involved in applying advanced gene editing technologies to support our gene correction programs and delivery discovery platform function.

Key Responsibilities:

  • Design, execute, and lead experiments using next-generation gene editing and epigenome editing strategies with CRISPR-based tools and beyond.
  • Advance gene correction applications for therapeutic and non-viral platform discovery projects through the design, implementation, optimization, and execution of molecular biology, cell biology, and NGS-based assays.
  • Support the discovery of novel LNP delivery solutions through in vitro and in vivo gene editing screens.
  • Work with primary in vitro cell culture disease models of lung epithelial cells.
  • Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate.
  • Analyze and present experimental data to a wide range of audiences.
  • Troubleshoot and dissect published literature to find novel solutions to resolve technical and/or biological hurdles.
  • Contribute as a key member of a cross-functional drug discovery team that includes gene correction, primary human biology, pharmacology, computational biology, bioanalytical, toxicology, and formulation capabilities.
  • Prepare SOPs, keep an excellent electronic lab notebook and record-keeping entries, and prepare reports and/or manuscripts for publication.
  • Manage one or more direct reports; mentor additions to the team.

Requirements:

  • PhD in molecular biology, cell biology, biological engineering, or related discipline with 4 years of experience in postdoctoral research and/or industry.
  • Subject matter expertise, with a proven track record of publications/patents, in gene editing, with a broad knowledge of gene editing applications.
  • Hands-on experience using gene editing tools including next-generation CRISPR systems (e.g. Prime or Base editors).
  • Deep expertise in analytic RNA or DNA assays to measure and analyze gene editing results.
  • Experience in utilizing bioinformatics tools and software for the analysis of gene editing readouts.
  • Experience in mammalian cell and tissue culturing is required.
  • Experience with viral or non-viral delivery platforms, preferably lipid nanoparticles (LNPs) (recommended).
  • Understanding of lung biology and/or rare lung disease (recommended).
  • Excellent verbal and written communication skills, with proven ability to write reports and/or articles for publication.
  • Advanced knowledge of statistical and genome analytical tools (GraphPad, R, SnapGene).
  • Excellent project leadership skills in driving for results and innovation; ability to execute within a matrixed organization.
  • Extremely organized and able to efficiently manage your time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
  • Highly collaborative, team-oriented, and considerate of the needs of others.
  • Desire to work in a fast-paced environment and contribute to developing the next generation of gene editing.

  • Postdoctoral Research Scientist

    4 weeks ago

    North East, United Kingdom ReCode Therapeutics, Inc. Full time

    Job SummaryWe are seeking a highly skilled Postdoctoral Project Research Scientist to join our team at ReCode Therapeutics, Inc. in Durham, NC. The successful candidate will be involved in applying advanced gene editing technologies to support our gene correction programs and delivery discovery platform function.This is a unique opportunity to be part of a...

  • Postdoctoral Research Associate in Biological Editing

    3 weeks ago

    East Hagbourne, United Kingdom The Rosalind Franklin Institute Full time

    Job DescriptionThe Rosalind Franklin Institute is a national research centre dedicated to creating new disruptive technologies that will revolutionize our understanding of the biological world. We are seeking a highly skilled Postdoctoral Research Associate to join our team in Biological Editing.Key ResponsibilitiesDevelop new chemistries for complex protein...

  • Senior Molecular Biologist Specialist

    2 weeks ago

    East Hagbourne, United Kingdom MRC Full time

    About the PositionThe MRC is seeking a highly skilled Molecular Biologist to join our team at the Mary Lyon Centre. As a Senior Molecular Biologist Specialist, you will be responsible for developing and implementing molecular biology techniques to support our research programs.You will design and conduct experiments, analyse data, and present findings to...

  • IP Protection Specialist for Advanced Engineering

    3 days ago

    South East London, United Kingdom Withers & Rogers Full time

    Withers & Rogers is a leading intellectual property law firm seeking an IP Protection Specialist for our Advanced Engineering group. This full-time, permanent position is based in one of our UK locations: Bristol, London, Sheffield, or Warwick.About UsWe are a dedicated and innovative team with over 140 years of experience. Our clients include renowned...

  • Patent Attorney

    4 weeks ago

    East Sheen, Greater London, United Kingdom Withers & Rogers Full time

    About UsWithers & Rogers is a leading intellectual property law firm with a strong presence in the UK, Europe, and globally. Our firm has a rich history of over 140 years, and we remain committed to delivering exceptional results for our clients.We pride ourselves on having a team of highly skilled patent and trade mark attorneys, support staff, and...

  • Disease Investigator Position in Research Triangle Park

    3 days ago

    North East, United Kingdom alphanumeric Full time

    Job OverviewWe are seeking an experienced Epidemiologist to join our team in the Research Triangle Park, NC area. As a Disease Investigator, you will work with our client of 20 years to improve lives through medical and pharmaceutical advancements.The estimated salary for this position is $120,000 - $180,000 per year, depending on experience.Key...

  • Clinical PhD Researcher

    2 weeks ago

    East Liverpool, Ohio, United Kingdom University of Liverpool Full time

    Academic OpportunityThe University of Liverpool is seeking a talented Clinical PhD researcher to join our team in the Liverpool Clinical PhD Programme. This fully funded PhD Fellowship Opportunity is ideal for UK-registered health professional graduates who are passionate about advancing their academic journey.Programme OverviewThe Liverpool Clinical PhD...

  • Clinical Research Midwife

    4 weeks ago

    East Liverpool, Ohio, United Kingdom Liverpool Women's NHS Foundation Trust Full time

    Job Title: Clinical Research Midwife - Research and DevelopmentThe Liverpool Women's NHS Foundation Trust is seeking a highly skilled and motivated Clinical Research Midwife to join their Research and Development team. The successful candidate will be responsible for assisting the Trust with its commitment to a sustained and dramatic increase in recruitment...

  • Pharmaceutical Development Polymer Scientist

    3 weeks ago

    East Kilbride, South Lanarkshire, United Kingdom Ferring Pharmaceuticals Full time

    Job SummaryFerring Pharmaceuticals is seeking a talented Polymer Chemist to join our innovative Pharmaceutical Product Development team. The successful candidate will be instrumental in developing and optimizing polymer-based materials for use in drug-device combination product development.About the RoleDevelop and Characterize: Develop and characterize...

  • Medical Director

    3 weeks ago

    East Midlands, United Kingdom University Hospitals of Derby and Burton NHS... Full time

    Deputy Medical Director - Research and DevelopmentWe are seeking an experienced professional to lead our Research and Development initiatives. The successful candidate will be responsible for developing and coordinating the Trust's Research Strategy, ensuring alignment with NHS priorities and securing sufficient funding to support research at all levels.Key...

  • Quantitative Researcher

    1 week ago

    South East England, United Kingdom Miller Maxwell Ltd Full time

    Quantitative Researcher- mid-frequency alpha - London - A leading trading firm in global financial markets is seeking an experienced Quantitative Researcher with a focus on mid-frequency alpha. This role offers a unique opportunity to work closely with seasoned traders and developers, leveraging cutting-edge technologies in a collaborative environment. ??...

  • High-Energy Laser Researcher

    4 weeks ago

    East Hagbourne, United Kingdom Industry Placements Full time

    High-Energy Laser ResearcherWe are seeking a highly motivated and enthusiastic researcher to join our team at the Centre for Advanced Laser Technology and Applications (CALTA). As a High-Energy Laser Researcher, you will be working on the development and improvement of our DiPOLE laser technology, which has achieved world-record-breaking performance.Your...

  • Academic Leader in Statistics and Probability

    4 weeks ago

    North East, United Kingdom The International Society for Bayesian Analysis Full time

    We are seeking a highly qualified Academic Leader in Statistics and Probability to join our team at Durham University. The successful candidate will contribute to the growth and development of our research and teaching programs, with a focus on Bayesian statistics and uncertainty quantification.The ideal candidate will have a strong background in statistics...

  • Researcher (Data Analysis)

    1 week ago

    South East England, United Kingdom Miller Maxwell Ltd Full time

    Quantitative Researcher- mid-frequency alpha - London - A leading trading firm in global financial markets is seeking an experienced Quantitative Researcher with a focus on mid-frequency alpha. This role offers a unique opportunity to work closely with seasoned traders and developers, leveraging cutting-edge technologies in a collaborative environment. ??...

  • Executive Director of Oceanographic Research

    4 weeks ago

    East Liverpool, Ohio, United Kingdom NATIONAL OCEANOGRAPHY CENTRE Full time

    NATIONAL OCEANOGRAPHY CENTREBOARD MEMBER OPPORTUNITYThe National Oceanography Centre is a world-leading research institution that undertakes cutting-edge research in oceanography and ocean measurement technology innovation. We work closely with government and business to translate our research into practical advice and applications.As a key player in the...

  • Senior Immunology Research Scientist

    4 weeks ago

    East Hagbourne, United Kingdom Barinthus Biotherapeutics Full time

    Immunology Research ScientistWe are seeking a highly skilled and organized Immunology Research Scientist to join our dynamic team at Barinthus Biotherapeutics. The successful candidate will be responsible for designing, planning, and executing immunology assays, with a focus on multiparameter flow cytometry and data analysis.Design and conduct immunology...

  • Quantum Computing Researcher

    4 weeks ago

    East Hagbourne, United Kingdom STFC Full time

    Job Title: Superconducting Qubit PhysicistLocation: Rutherford Appleton Laboratory, Harwell Campus, Oxfordshire, UKContract Type: Up to 2 Permanent PositionsSalary: Band E S1, £53,818 - £59,199 (gross per annum dependent on experience)Hours: Full-time (We understand the importance of work-life balance, and are happy to discuss the possibility of flexible...

  • Management Studies Community Development Specialist

    4 weeks ago

    North East, United Kingdom Society for the Advancement of Management Studies Full time

    Developing the Management Studies Community: A Call for Funding ApplicationsSAMS, the Society for the Advancement of Management Studies, invites applications for funding to support events or activities that benefit the global management studies community.Priority will be given to proposals that contribute to the development of doctoral students and/or early...

  • Strategic Sourcing Specialist

    4 weeks ago

    North East, United Kingdom University System of NH Full time

    The University System of New Hampshire seeks a Strategic Sourcing Specialist to shape strategic sourcing goals and enhance flexibility, financial performance, and reduce costs. The ideal candidate will optimize sourcing strategies, lead spend analytics, and manage procurement data consolidation. They will collaborate on advanced data analysis, leverage...

  • Clinical Scientist

    4 weeks ago

    North Shields, North Tyneside, United Kingdom Northumbria Healthcare NHS Foundation Trust Full time

    We are seeking a highly skilled Clinical Scientist to join our team at Northumbria Healthcare NHS Foundation Trust. As a Clinical Scientist, you will be responsible for performing advanced healthcare science activities, primarily within the area of clinical physiological assessment.Key responsibilities include:Providing highly specialist advice and training...