Bioinformatics Specialist

1 month ago


Cambridge, Cambridgeshire, United Kingdom Origin Sciences Full time
Job Title: Bioinformatician

Origin Sciences is a pioneering biotechnology company based in the UK, dedicated to developing innovative medical devices for clinical trials. Our mission is to create a minimally invasive and accurate diagnostic for Colorectal Cancer (CRC), enabling the NHS to focus on patients with serious pathologies.

We are seeking a highly skilled Bioinformatician to join our Data Team and play a pivotal role in optimizing sample and data processing, as well as validating bioinformatic pipelines. The successful candidate will be responsible for developing and validating bioinformatics pipelines to integrate with our current suite of pipelines, written in Nextflow.

Main Responsibilities:
  • Develop and implement bioinformatics pipelines to process omics data, ensuring high-quality results.
  • Validate pipelines in the context of each individual use case, ensuring accuracy and reliability.
  • Optimize pipelines for high-throughput processing, ensuring efficient data analysis.
  • Perform technical analysis to evaluate data quality and work closely with the lab team to optimize wet lab processes.
  • Provide bioinformatics input to R&D projects, ensuring the development of innovative diagnostic solutions.
Requirements:
  • PhD or Master's degree in Bioinformatics, Genetics, Mathematics, Statistics, Engineering, Computer Sciences, or a relevant discipline.
  • Experience with Nextflow workflow language and scientific programming in Python and/or R.
  • Ability to create customized bioinformatics pipelines for each individual use case.
  • Understanding of data management best practices and ability to critically evaluate analytical methodologies and results.
Desirable:
  • Experience implementing unit tests to bioinformatics pipelines.
  • Previous experience analyzing cancer-associated signatures from NGS or sequencing-based methylation data.
  • Experience working with data derived from clinical trial samples.
Benefits:
  • 25 days holiday
  • Pension contribution


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