Postdoctoral Researcher

4 weeks ago


Oxford, Oxfordshire, United Kingdom University of Oxford Full time
Postdoctoral Researcher Opportunity

We are seeking a highly motivated Postdoctoral Researcher to join our team at the University of Oxford. The successful candidate will work alongside structural biologists and molecular biologists to discover novel therapeutic approaches to various human diseases.

The Centre for Medicines Discovery (CMD) is a leading research institution that aims to de-risk novel therapeutic approaches and discover novel agents fit for further discovery investment. As a Postdoctoral Researcher, you will be responsible for developing biochemical, biophysical, and target engagement assays, utilising them to identify and evaluate ligands for the proteins of interest.

You will execute bench-level experiments, write protocols, design experimental plans, develop new scientific techniques, and contribute ideas for new research projects. You will also use and manage specialist scientific equipment in a laboratory environment, such as Echo (automated liquid handling), Pherastar plate readers, Biacore (SPR), ITC, Octet (BLI), and RapidFire mass spectrometry (Agilent).

To be successful in this role, you will hold a PhD/DPhil (or be close to completion) in Biochemistry, Biophysics, Pharmacology, or a similar subject, along with a background in protein biochemistry/enzymology with experience in the determination of drug mechanism of action and analysis of thermodynamics and kinetics.

Excellent interpersonal, oral, and written communication skills are essential, along with the ability to collaborate effectively within a dynamic team and matrix environment.

This is a full-time, fixed-term contract until 31 July 2026, and the position is funded by the Department. The successful candidate will be required to upload a supporting statement and CV as part of their online application.

Please note that only applications received before 12 midday on Tuesday 5 November 2024 will be considered. Interviews will be held the week commencing 18 November 2024.



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