Bioinformatics Developer

2 days ago


Hinxton, United Kingdom Embl-Ebi Full time
About the Role

This is an exciting opportunity to contribute to the development of highly-used open-source bioinformatics resources at the European Bioinformatics Institute (EMBL-EBI). As a Bioinformatics Developer, you will play a key role in designing and developing user-friendly software and tools for the functional annotation and prioritization of genomics variants.

Key Responsibilities
  • Develop and maintain tools for the functional annotation and prioritization of genomics variants, including Ensembl VEP.
  • Develop, maintain, and run efficient methods for managing and accessing large-scale variation data for community use and to power the Ensembl websites.
  • Investigate and integrate new sources of genomic variation, phenotype association data, and prediction tools.
  • Collaborate with members of the wider Ensembl team on specific development projects and to coordinate regular data and software releases.
  • Liaise with other groups at EMBL-EBI and external collaborators to add new functionalities to our tools and agree on community standards for data representation.
  • Support our users and present our work at internal meetings and scientific conferences.
Requirements
  • Experience in the design and development of user-friendly software or code, with proficiency in Python.
  • Experience of managing and analyzing large-scale genomics data, preferably genetic variation data.
  • Experience working with large-scale relational databases, preferably MySQL.
  • Proficiency working in a UNIX/Linux environment.
  • Excellent attention to detail and the ability to deliver a high-quality product to agreed deadlines.
  • Good communication and interpersonal skills.
  • Scientific curiosity and initiative.
Desirable Skills
  • Familiarity with the Ensembl resources, in particular Ensembl VEP.
  • Experience working in a HPC bioinformatics environment, ideally creating and managing efficient large-scale data analysis pipelines using NextFlow.
  • Experience collaborating on projects, working with colleagues from different disciplines, and using version control platforms, ideally GitHub.
  • Design and development of REST or GraphQL APIs.
  • Experience with a range of bioinformatics or statistical tools and data formats.
  • Familiarity with another programming language such as Perl and/or C.
About EMBL-EBI

EMBL-EBI is a world-leading research institute in bioinformatics and computational biology. We are part of the European Molecular Biology Laboratory (EMBL) and are located in Hinxton, Cambridge, UK. Our mission is to provide the global scientific community with access to high-quality bioinformatics tools, data, and services.


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