Senior Scientist, Technology Development

1 month ago

Cambridge, Cambridgeshire, United Kingdom ZipRecruiter Full time

Job Title: Senior Scientist, Technology Development

Job Summary:

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development.

The company is currently seeking a Senior Scientist to join its Structural Biology Team. The successful candidate will be responsible for obtaining high-quality protein structural data to positively impact a wide range of drug discovery programs, both internal and partnered.

Key Responsibilities:

  • Drive structural biology-related activities of Discovery programs
  • Solve protein structures employing Protein crystallography or CryoEM methods
  • Critical interpretation and presentation of structural data to internal and external project teams to aid target understanding
  • Work with Protein Sciences and Biophysics teams to validate biochemical data relevant for structure determination and target-specific assays
  • Prepare materials for publication where structural data has been produced (figure, compiling data for PDB deposition etc.)

Requirements:

  • Educated in structural biology or equivalent qualification/experience
  • Capable of independently designing and safely executing wet lab experiments
  • Experience in biochemical and biophysical characterization of proteins, specifically in construct design and sample quality evaluation
  • Experience of working in a pharmaceutical/biotechnology/drug discovery setting
  • Experience using software/computational methods to aid structure-based drug design
  • Diligence in documenting work and understanding of data integrity importance

What We Offer:

  • State-of-the-art campus environment with on campus restaurant and Montessori nursery
  • Flexible working environment
  • Competitive reward including annual company bonus
  • Employee recognition schemes
  • 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually
  • Employer contribution to pension (employee does not have to contribute)
  • Life assurance cover 4x basic salary
  • Private Medical Insurance, including optical and dental cover
  • Employee assistance program
  • Health Cash Plan
  • Access to company subsidized gym membership
  • Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc
  • Cycle to work scheme

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve.

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